Traditional cognitive neuroscience uses task-evoked activations to map neurocognitive processes (and information) to brain regions; however, how those processes are generated is unknown. We developed activity flow mapping to identify and empirically validate network mechanisms underlying the generation of neurocognitive processes. This approach models the movement of task-evoked activity over brain connections to predict task-evoked activations. We present a protocol for using the Brain Activity Flow Toolbox (https://colelab.github.io/ActflowToolbox/) to identify network mechanisms underlying neurocognitive processes of interest. For complete details on the use and execution of this protocol, please refer to Cole et al., 2021.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808261PMC
http://dx.doi.org/10.1016/j.xpro.2021.101094DOI Listing

Publication Analysis

Top Keywords

activity flow
16
neurocognitive processes
12
flow mapping
8
brain activity
8
flow toolbox
8
task-evoked activations
8
network mechanisms
8
mechanisms underlying
8
protocol activity
4
flow
4

Similar Publications

Purpose: To investigate the effect of Rho-associated protein kinase (ROCK) inhibitor Y27632 on bioenergetic capacity and resilience of corneal endothelial cells (CECs) under metabolic stress.

Methods: Bovine CECs (BCECs) were treated with Y27632 and subjected to bioenergetic profiling using the Seahorse XFp Analyzer. The effects on adenosine triphosphate (ATP) production through oxidative phosphorylation and glycolysis were measured.

View Article and Find Full Text PDF

Metabolic activity controls the emergence of coherent flows in microbial suspensions.

Proc Natl Acad Sci U S A

January 2025

Experimental Physics V, Department of Physics, University of Bayreuth, D-95447 Bayreuth, Germany.

Photosynthetic microbes have evolved and successfully adapted to the ever-changing environmental conditions in complex microhabitats throughout almost all ecosystems on Earth. In the absence of light, they can sustain their biological functionalities through aerobic respiration, and even in anoxic conditions through anaerobic metabolic activity. For a suspension of photosynthetic microbes in an anaerobic environment, individual cellular motility is directly controlled by its photosynthetic activity, i.

View Article and Find Full Text PDF

Purpose: Elevated methylglyoxal (MGO) levels and altered immune cell responses are observed in diabetes. MGO is thought to modulate immune cell activation. The current study investigated whether fasting or post-glucose-load plasma MGO concentrations are associated with circulating immune cell counts and activation in a large cohort study.

View Article and Find Full Text PDF

This study expands the original two-dimensional carbon footprint model into a three-dimensional model form. Introduce two indicators of carbon footprint depth (CF) and size (CF) to form a three-dimensional carbon footprint model (CF), which is used to respectively represent the occupation and consumption of natural capital reserves by human activities' carbon emissions. Based on the 3D carbon footprint model, this paper calculated the CF, CF, and CF for four different urban agglomerations of China (BTH, YRD, PRD, and CY) spanning from 2000 to 2017.

View Article and Find Full Text PDF

Diabetes mellitus (DM) is a global health concern with a rising incidence, particularly in aging populations and those with a genetic predisposition. Over time, DM contributes to various complications, including nephropathy, retinopathy, peripheral arterial disease (PAD), and neuropathy. Among these, diabetic neuropathy and PAD stand out due to their high prevalence and significant impact on patients' quality of life.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!