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Serum IgG Responses to gp15 and gp40 Protein-Derived Synthetic Peptides From . | LitMetric

Serum IgG Responses to gp15 and gp40 Protein-Derived Synthetic Peptides From .

Front Cell Infect Microbiol

Departamento de Ciencias Químico Biológicas, Universidad de Sonora, Hermosillo, Mexico.

Published: April 2022

spp. are responsible for moderate to severe diarrhea, mainly in children and immunocompromised patients. Using ELISA, the recognition of synthetic peptides generated from the sequences of the gp40 and gp15 proteins by serum IgM and IgG antibodies from patients infected (cases) with , , and , and uninfected individuals (controls) was evaluated. A statistically significant difference (p = 0.0025) was found in terms of the recognition of peptides A133 and A32 between cases and controls. Additional studies are necessary to understand the potential of these peptides as vaccine candidates.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807513PMC
http://dx.doi.org/10.3389/fcimb.2021.810887DOI Listing

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