Aims: The cemented Oxford unicompartmental knee arthroplasty (OUKA) features two variants: single and twin peg OUKA. The purpose of this study was to assess the stability of both variants in a worst-case scenario of bone defects and suboptimal cementation.
Methods: Single and twin pegs were implanted randomly allocated in 12 pairs of human fresh-frozen femora. We generated 5° bone defects at the posterior condyle. Relative movement was simulated using a servohydraulic pulser, and analyzed at 70°/115° knee flexion. Relative movement was surveyed at seven points of measurement on implant and bone, using an optic system.
Results: At the main fixation zone, the twin peg shows less relative movement at 70°/115°. At the transition zone, relative movements are smaller for the single peg for both angles. The single peg shows higher compression at 70° flexion, whereas the twin peg design shows higher compression at 115°. X-displacement is significantly higher for the single peg at 115°.
Conclusion: Bony defects should be avoided in OUKA. The twin peg shows high resilience against push-out force and should be preferred over the single peg. Cite this article: 2022;11(2):82-90.
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http://dx.doi.org/10.1302/2046-3758.112.BJR-2020-0507.R2 | DOI Listing |
RSC Adv
November 2024
Jiangxi Province Key Laboratory of Functional Crystalline Materials Chemistry, School of Chemistry and Chemical Engineering, Jiangxi University of Science and Technology Ganzhou 341000 China
Electroplating additives play a key role in enhancing the physical and chemical performances of electrodeposited copper foils. Currently, a lot of research on polyethylene glycol (PEG) additives has been reported on the metallisation interconnections for printed circuit boards (PCBs); however, research on its applications for electrodeposited copper foils is rarely documented. Herein, high-quality copper foils with high tensile strength (433.
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December 2024
Department of Ophthalmology, Division of Head, Neck and Reconstructive Surgery, Oslo University Hospital, Oslo, Norway.
Dry eye disease (DED) is a highly prevalent condition, resulting in reduced quality of life, lower participation in social life and impaired work efficiency. Hydroxypropyl methylcellulose (HPMC) is a cellulose-based viscosity-enhancing agent and is one of the most popular therapeutic ingredients in artificial tears. This review aims to evaluate the literature on the efficacy and safety of HPMC used in the treatment of DED.
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June 2024
National Metal and Materials Technology Center (MTEC), National Science and Technology Development Agency, Khlong-Nueng, Khlong Luang, Pathumthani 12120, Thailand.
This study presents a method for the self-formation of lignin particles within a polylactic acid (PLA) matrix during melt-extrusion, eliminating the need for separation and drying steps typically associated with submicro-size lignin particles. This method effectively mitigates the problem of agglomeration often associated with the drying step. Softwood kraft lignin, guaiacyl lignin (GL-lignin), was dissolved in low-molecular-weight poly(ethylene glycol) (PEG) and was introduced into a twin-screw extruder using a liquid feeder.
View Article and Find Full Text PDFEur J Pharm Biopharm
July 2024
Department of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, University, MS 38677, USA; Pii Center for Pharmaceutical Technology, The University of Mississippi, University, MS 38677, USA. Electronic address:
J Exp Bot
September 2024
Department of Biotechnology, Central University of Haryana, Mahendragarh, Haryana, 123031, India.
Prime editors are reverse transcriptase (RT)-based genome-editing tools that utilize double-strand break (DSB)-free mechanisms to decrease off-target editing in genomes and enhance the efficiency of targeted insertions. The multiple prime editors that have been developed within a short span of time are a testament to the potential of this technique for targeted insertions. This is mainly because of the possibility of generation of all types of mutations including deletions, insertions, transitions, and transversions.
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