AI Article Synopsis
- - Antibiotics like cefazolin can cause rare side effects, including neuromuscular blockade (NMB), which leads to paralysis-like symptoms.
- - NMB is not commonly recognized in neurosurgery and spinal surgery, making it a confusing issue for healthcare providers in those fields.
- - This report discusses a specific case where a patient experienced periodic quadriplegia after surgery due to NMB from a prophylactic antibiotic, along with a literature review on the topic.
Article Abstract
The use of antibiotics can, in rare cases, induce neuromuscular blockade (NMB), resulting in paralytic symptoms. Although such antibiotic-induced NMB has been described in the anaesthesiology and infectious disease literature, it is an unfamiliar clinical entity in the fields of neurosurgery and spinal surgery. Herein, we report a case of periodic quadriplegia due to NMB induced by perioperative prophylactic antibiotic of cefazolin, resulting in highly confusing paralytic symptoms during the acute postoperative phase of cervical laminoplasty, together with a review of the relevant literature.
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| http://dx.doi.org/10.1007/s00701-022-05148-3 | DOI Listing |
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