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Voxel-Based Morphometry and Subfield Volumetry Analysis Reveal Limbic System Involvement in Tinnitus.
J Neuroimaging
January 2025
Department of Otorhinolaryngology, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Background And Purpose: Tinnitus is a condition in which individuals perceive sounds, such as ringing or buzzing, without any external source. Although the exact cause is not fully understood, recent studies have indicated the involvement of nonauditory brain structures, including the limbic system. We aimed to compare the volumes of specific brain structures between patients with tinnitus and controls.
View Article and Find Full Text PDFAltered functional network topology properties to detect anxiety and depression caused by Crohn's disease and disease severity.
Brain Res Bull
December 2024
Department of Radiology, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou Meddical Center, Nanjing Medical University, No. 68 Gehu Middle Road, Changzhou, Jiangsu Province 213000, China. Electronic address:
Objective: Here we investigated changes in topological properties of functional brain networks among individuals with Crohn's disease (CD) and to determine whether these changes are related to CD severity, as well as CD-associated anxiety and depression, which are regulated by the brain-gut axis mechanism.
Methods: In total, 31 individuals with CD, 21 with irritable bowel syndrome (IBS), and 20 healthy controls underwent functional magnetic resonance imaging. Individuals with CD or IBS were also evaluated using the Hospital Anxiety and Depression Scale-Anxiety (HADS-A) and Depression (HADS-D) scales, as well as the simple endoscopic score for CD (SES-CD).
Research Review: Shared and distinct structural and functional brain alterations in adolescents with major depressive disorder' - a multimodal meta-analysis.
J Child Psychol Psychiatry
December 2024
Department of Radiology and Huaxi MR Research Center (HMRRC), Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, China.
Background: Neuroimaging studies have identified brain structural and functional alterations in adolescents with major depressive disorder (MDD); however, the results are inconsistent, and whether patients exhibit spatially convergent structural and functional brain abnormalities remains unclear.
Methods: We conducted voxel-wise meta-analysis of voxel-based morphometry (VBM) and resting-state functional studies, respectively, to identify regional gray matter volume (GMV) and brain activity alterations in adolescent MDD patients. Multimodal analysis was performed to examine the overlap of regional GMV and brain activity alterations.
Graph analysis of guilt processing network highlights links with subclinical anxiety and self-blame.
Soc Cogn Affect Neurosci
December 2024
Neuropsychology and Functional Neuroimaging Group, Department of Basic and Clinical Psychology and Psychobiology, Jaume I University, Castellon de la Plana 12-006, Spain.
Maladaptive forms of guilt, such as excessive self-blame, are common characteristics of anxiety and depressive disorders. The underlying network consists of multiple associative areas, including the superior anterior temporal lobe (sATL), underlying the conceptual representations of social meaning, and fronto-subcortical areas involved in the affective dimension of guilt. Nevertheless, despite understanding the circuitry's anatomy, network-level changes related to subclinical anxiety and self-blaming behaviour have not been depicted.
View Article and Find Full Text PDFNeuropsychological performances and brain perfusion patterns in patients with first episode psychosis.
J Psychiatr Res
November 2024
Department of Psychiatry, School of Health Sciences, Faculty of Medicine, University of Ioannina, Greece. Electronic address:
Abnormalities in cognition are a pronounced feature in primary psychotic disorders and may appear long before the manifestation of the first-episode psychosis (FEP). Although brain functional changes may precede structural alterations, brain perfusion patterns in FEP and most importantly their correlations with cognition remain poorly understood. In the present study we assessed neurocognitive functions and regional cerebral blood flow (rCBF) in 53 patients with a diagnosis of FEP.
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