Salmonella respiration turns the tables on propionate.

Trends Microbiol

Division of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California San Diego, La Jolla, CA 92093, USA; Center for Microbiome Innovation, University of California San Diego, La Jolla, CA 92093, USA; Chiba University-UC San Diego Center for Mucosal Immunology, Allergy, and Vaccines (CU-UCSD cMAV), La Jolla, CA 92093, USA. Electronic address:

Published: March 2022

Intestinal pathogens must combat host and microbiota-associated resistance to establish an infection. A new study (Shelton et al.) highlights how Salmonella manipulates the mammalian host to produce anaerobic respiratory electron acceptors, allowing catabolism of propionate and providing a competitive edge to Salmonella residing in the gut.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000922PMC
http://dx.doi.org/10.1016/j.tim.2022.01.011DOI Listing

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