AI Article Synopsis
- Research shows a connection between neighborhood environments and health outcomes, though the biological reasons for this link are unclear.
- A systematic review analyzed 19 studies exploring the relationship between neighborhood context and telomere length (TL), which is a biological marker that shortens with cell division and is associated with aging and chronic stress.
- While results were inconsistent regarding neighborhood disadvantage and TL, several studies indicate that negative perceptions of neighborhood problems may be related to shorter telomere length, highlighting the importance of community perceptions in health vulnerabilities.
Article Abstract
A growing body of research demonstrates the association between neighborhood context and health. The underlying biological mechanisms of this association are not fully understood. We conducted a systematic review of studies that investigated the association between neighborhood context and telomere length (TL), a DNA-protein complex that shortens after cell division. Short TL is linked to age-related diseases and may be impacted by chronic stress. Nineteen eligible articles identified through PubMed and Scopus met inclusion criteria. Results demonstrated inconsistent support for the relationship between neighborhood disadvantage and short TL. However, findings across several studies provide evidence for an inverse association between perceived neighborhood problems and TL, suggesting that TL may be an important factor in understanding health vulnerabilities associated specifically with negative perceptions of the neighborhood context.
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| http://dx.doi.org/10.1016/j.healthplace.2022.102746 | DOI Listing |
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