AI Article Synopsis
- The study investigates the various factors influencing medication adherence among diabetes patients in different Asian regions, acknowledging that these factors can vary greatly based on social and cultural contexts.
- A systematic literature review was performed using seven databases to identify and classify these determinants, yielding 26 relevant articles specifically focusing on type 2 diabetes patients from countries like India.
- Findings reveal that medication adherence rates are low to moderate, with 51 specific factors identified and categorized into four distinct groups, primarily highlighting the impact of patient-related demographics and perceptions on adherence.
Article Abstract
Background: The determinants of medication adherence in people with diabetes may differ between populations of an area due to social environment, cultural beliefs, socioeconomic conditions, education, and many other factors differences.
Objective: Therefore, this study aims to explore, identify and classify the determinants of medication adherence in several Asian regions.
Methods: A systematic literature review was conducted to gain insight into the determinants of medication adherence. Seven relevant databases (EBSCO, ProQuest, PubMed, ScienceDirect, Scopus, Wiley, dan Taylor and Francis) and hand searching methods were conducted from January 2011 to December 2020. Keywords were compiled based on the PICO method. The selection process used the PRISMA guidelines based on inclusion, and the quality was assessed using Crowe's critical assessment tool. Textual summaries and a conceptual framework model of medication adherence were proposed to aid in the understanding of the factors influencing medication adherence.
Results: Twenty-six articles from countries in several Asian regions were further analyzed. Most studies on type 2 diabetes patients in India used the MMAS-8 scale, and cross-sectional study is the most frequently used research design. The medication adherence rate among diabetic patients was low to moderate. Fifty-one specific factors identified were further categorized into twenty-three subdomains and six domains. Furthermore, the determinants were classified into four categories: inconsistent factors, positively related factors, negatively related factors, and non-associated factors. In most studies, patient-related factors dominate the association with medication adherence. This domain relates to patient-specific demographics, physiological feelings, knowledge, perceptions and beliefs, comorbidities, and other factors related to the patient. Several limitations in this review need to be considered for further research.
Conclusion: Medication adherence to diabetic therapy is a complex phenomenon. Most determinants produced disparate findings in terms of statistical significance. The identified factors can serve various goals related to medication adherence. Policymakers and health care providers should consider patient-related factors.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803611 | PMC |
| http://dx.doi.org/10.2147/PPA.S347079 | DOI Listing |
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