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Predicting and Ranking Diabetic Ketoacidosis Risk among Youth with Type 1 Diabetes with a Clinic-to-Clinic Transferrable Machine Learning Model.
Diabetes Technol Ther
January 2025
Children's Mercy Kansas City, Endocrinology, Kansas City, Missouri, USA.
To use electronic health record (EHR) data to develop a scalable and transferrable model to predict 6-month risk for diabetic ketoacidosis (DKA)-related hospitalization or emergency care in youth with type 1 diabetes (T1D). To achieve a sharable predictive model, we engineered features using EHR data mapped to the T1D Exchange Quality Improvement Collaborative's (T1DX-QI) data schema used by 60+ U.S.
View Article and Find Full Text PDFEffects of cross-linked/acetylated tapioca starches on the gelling properties, rheological behaviors and microstructure of myofibrillar protein gels: Perspective on molecular interactions and phase transition.
Meat Sci
February 2025
College of Food Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, China. Electronic address:
Article Synopsis
- - The study examined how varying amounts of cross-linked tapioca starch (CTS) or acetylated tapioca starch (ATS) affect the characteristics and properties of myofibrillar protein (MP) gels.
- - Results indicated that both CTS and ATS improved gel strength and water retention in MP gels, with CTS showing superior results due to its higher viscosity and ability to create a smoother gel matrix.
- - Molecular interactions between MP and modified tapioca starches, such as hydrophobic interactions and disulfide bonds, were key to transitioning the gel's continuous phase, enhancing the overall quality of meat products.
Changes of structural characteristics, functional properties and volatile compounds of Tenebrio molitor larvae protein after sustainable defatting process: Influence of the different volume ratios of n-hexane to ethanol.
Food Res Int
November 2024
College of Food Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, China. Electronic address:
This work aimed to study the effect of defatting via the mixture of n-hexane and ethanol under different volume ratio on the changes of structural characteristics, functional properties and volatile compounds of Tenebrio molitor larvae protein (TMLP). The results showed that 1:0.6 vol ratio of n-hexane to ethanol rendered the highest defatting rate (P < 0.
View Article and Find Full Text PDFApplication of lysine as a potential alternative to sodium salt in frankfurters: With emphasis on quality profile promotion and saltiness compensation.
Meat Sci
November 2024
College of Food Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, China; Heilongjiang Green Food Science & Research Institute, Harbin, Heilongjiang 150028, China. Electronic address:
This study aimed to investigate the effect of lysine (Lys) on quality profile promotion and saltiness compensation in reduced‑sodium salt frankfurters. The results showed that the cooking loss of reduced‑sodium salt frankfurters decreased from 5.63 to 3.
View Article and Find Full Text PDFBiophysical essentials - A full stack open-source software framework for conserved and advanced analysis of patch-clamp recordings.
Comput Methods Programs Biomed
October 2024
Institute of Physiology, Medical University of Innsbruck, Innsbruck, Austria; Omiqa Bioinformatics GmbH, Berlin, Germany.
Background And Objectives: Patch-Clamp recordings allow for in depth electrophysiological characterization of single cells, their general biophysical properties as well as characteristics of voltage- and ligand-gated ionic currents. Different acquisition modes, such as whole-cell patch-clamp recordings in the current or voltage clamp configuration, capacitance measurements or single channel recordings from cultured cells as well as acute brain slices are routinely performed for these purposes. Nevertheless, multipurpose transparent and adaptable software tools to perform reproducible state-of-the-art analysis of multiple experiment types and to manage larger sets of experimental data are currently unavailable.
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