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http://dx.doi.org/10.1038/s41386-021-01216-x | DOI Listing |
Kidney Res Clin Pract
January 2025
Department of Radiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
Background: We aimed to explore changes in decision-related brain microstructure, brain functional activities, and functional connectivity, and their correlations with cognitive function in end-stage kidney disease (ESKD) patients undergoing peritoneal dialysis (PD). Furthermore, the impact of dialysis on these changes was examined.
Methods: Thirty ESKD patients undergoing PD, 20 chronic kidney disease (CKD) stage 5 patients without dialysis (predialysis CKD stage 5), and 30 healthy controls (HC) were recruited for the study.
Front Aging Neurosci
January 2025
Department of Psychiatry, Affiliated Kangning Hospital of Ningbo University, Ningbo, China.
Background: Studies have shown the clinical effects of repetitive transcranial magnetic stimulation (rTMS) on depression in Alzheimer's disease (AD). However, the underlying mechanisms remain poorly understood. The measurement of brain activation links neurobiological and functional aspects but is challenging in patients with dementia.
View Article and Find Full Text PDFQuant Imaging Med Surg
January 2025
Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Background: Cognitive decline may occur in patients with end-stage renal disease (ESRD), and is particularly severe in patients with ESRD undergoing hemodialysis; however, the mechanism of this relationship between cognitive decline and ESRD is unclear. Cortical-based structural and functional analysis can be used to understand these cortical changes and their relationship with cognitive decline in non-dialysis and maintenance dialysis ESRD patients. This study aimed to examine whether there was any correlation between alterations in cortical and resting-state function changes and cognitive decline in patients diagnosed with ESRD.
View Article and Find Full Text PDFAlzheimers Dement (Amst)
January 2025
Introduction: Cross-sectional resting-state functional magnetic resonance imaging (rsfMRI) studies have revealed altered complexity with advanced Alzheimer's disease (AD) stages. The current study conducted longitudinal rsfMRI complexity analyses in AD.
Methods: Linear mixed-effects (LME) models were implemented to evaluate altered rates of disease progression in complexity across disease groups.
Behav Brain Res
January 2025
Department of Neurosurgery, Hannover Medical School, Carl-Neuberg-Straße 1, Hannover 30625, Germany; Cluster of Excellence Hearing4all, German Research Foundation, Hannover, Germany; Center for Systems Neuroscience (ZSN) Hannover, Hannover 30559, Germany.
Background: The three-class oddball paradigm allows to investigate the processing of behaviorally relevant and irrelevant auditory stimuli. In humans, event-related potentials (ERPs) are used as neural correlate of behavior. We recorded local field potentials (LFPs) within the medial prefrontal cortex (mPFC) in rats during three-class and passive two-class oddball paradigms and analyzed the ERPs focusing on similarities to human recordings.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!