AI Article Synopsis
- Immunoglobulin-G4-related disease (IgG4-RD) is a rare inflammatory disorder affecting multiple organs, with unclear treatment approaches for coronary artery involvement.
- A case report describes mass lesions around the coronary arteries, specifically showing moderate stenosis in the right coronary artery (RCA) and a fractional flow reserve (FFR) measurement of 0.76.
- Following steroid treatment, both the mass lesions and FFR improved, rising from 0.76 to 0.86, indicating that steroids may be an effective therapy for managing coronary artery issues related to IgG4-RD.
Article Abstract
Immunoglobulin-G4-related disease (IgG4-RD) is a multi-organ systemic inflammatory disorder. The ideal treatment of coronary artery involvement in IgG4-RD remains uncertain due to its rarity. We herein report a case of coronary artery involvement with IgG4-RD, wherein mass lesions surrounded the coronary arteries with a moderate stenosis lesion in the right coronary artery (RCA). The fractional flow reserve (FFR) of the RCA was 0.76. After steroid therapy, the mass lesions around the coronary arteries improved. The FFR of the RCA also improved from 0.76 to 0.86. These findings suggest the efficacy of using steroid therapy for coronary artery involvement with IgG4-RD.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866778 | PMC |
| http://dx.doi.org/10.2169/internalmedicine.7880-21 | DOI Listing |
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