Current methods for identification of oxygenator clotting during prolonged extracorporeal life support include visual inspection, evaluation of oxygenator resistance and oxygen exchange performance, and assessment of clotting-related laboratory parameters. However, these observations do not provide a quantitative assessment of oxygenator clot formation. By measuring changes in the dynamic oxygenator blood volume this study aimed to evaluate the relation to oxygenator resistance and oxygen transfer performance. Sixty-seven oxygenators were studied during adult extracorporeal life support. Oxygenator blood volume, oxygenator resistance, and oxygen transfer efficiency were monitored. Oxygenator blood volume decreased with increasing runtime (r = -0.462; p <0.001). There was a statistically significant, fair negative correlation between oxygenator blood volume and oxygenator resistance (r = -0.476; p<0.001) in all oxygenators, which became stronger analyzing only exchanged oxygenators (r = -0.680; p<0.001) and oxygenators with an oxygenator blood volume <187 mL (r = 0.831; p<0.001). No relevant correlation between oxygenator blood volume and O2 transfer was found. Oxygenator blood volume declined over time and was clearly associated with an increasing oxygenator resistance during prolonged extracorporeal life support, though O2 transfer was less affected.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809600 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0263360 | PLOS |
Publication Analysis
Top Keywords
Similar Publications
Hyperbaric oxygen therapy in the treatment of severe gastric laceration with active bleeding: A case report.
World J Gastrointest Endosc
January 2025
Department of Gastroenterology, Shenzhen People's Hospital (Jinan University of Second Clinical Medical Sciences), Shenzhen 518020, Guangdong Province, China.
Background: Endoscopic therapy is the primary approach for treating Mallory-Weiss syndrome, particularly under conditions of mucosal protection and gastric acid suppression. However, for a subset of patients who cannot undergo endoscopic intervention or for whom such treatment proves ineffective, alternative measures like arterial embolization or surgical intervention may be required. While hyperbaric oxygen therapy (HBOT) has been applied across a range of medical conditions, its application in managing hemorrhage due to gastric tears remains undocumented.
View Article and Find Full Text PDFPrediction of delirium occurrence using machine learning in acute stroke patients in intensive care unit.
Front Neurosci
January 2025
Department of Biomedical Systems Informatics, Yonsei University College of Medicine, Seoul, Republic of Korea.
Introduction: Delirium, frequently experienced by ischemic stroke patients, is one of the most common neuropsychiatric syndromes reported in the Intensive Care Unit (ICU). Stroke patients with delirium have a high mortality rate and lengthy hospitalization. For these reasons, early diagnosis of delirium in the ICU is critical for better patient prognosis.
View Article and Find Full Text PDFImpact of high hemoglobin levels on carotid artery intima-media thickness and its predictive value for hypertension in high-altitude areas: a real-world study.
Front Cardiovasc Med
January 2025
Hyperbaric Oxygen, Chengdu First People's Hospital, Chengdu, Sichuan, China.
Background And Purpose: The hemoglobin levels in the peripheral blood of individuals living at high altitudes are significantly higher than normal levels. These levels are closely associated with atherosclerosis and cardiovascular events. This study aimed to investigate the correlation between hemoglobin levels in the peripheral blood and hypertension in high-altitude regions, providing a basis for preventing and treating primary hypertension in these regions.
View Article and Find Full Text PDFChallenges during cardiac arrest in pregnancy.
Resusc Plus
January 2025
Department of Emergency Medicine, University Hospital Gasthuisberg, Leuven, Belgium.
A 36-year-old woman at 23 weeks and 3 days of gestation experienced a witnessed cardiopulmonary collapse. Bystander cardiopulmonary resuscitation (CPR) was initiated immediately. After advanced life support, she was transferred under mechanical CPR to a hospital for extracorporeal membrane oxygenation (ECMO).
View Article and Find Full Text PDFA nomogram for predicting neonatal acute respiratory distress syndrome in patients with neonatal pneumonia after 34 weeks of gestation.
Front Pediatr
January 2025
Department of Pediatrics, Dandong Central Hospital, China Medical University, Dandong, China.
Objective: To establish a prediction nomogram for early prediction of neonatal acute respiratory distress syndrome (NARDS).
Methods: This is a retrospective cross-sectional study conducted between January 2021 and December 2023. Clinical characteristics and laboratory results of cases with neonatal pneumonia were compared in terms of presence of NARDS diagnosis based on the Montreux Definition.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!