Objective: Neurologic bowel incontinence and dysfunction are common with Cauda Equina Syndrome (CES). The study objective was to evaluate the efficacy of Peristeen Anal Irrigation System (PAIS) in people with CES.
Design: Clinical Trial.
Setting: Spinal Cord Rehabilitation outpatient clinic at the Health Sciences Centre in Winnipeg.
Methods: Twelve participants with a mean age of 46.2 years (range 34-72 years, 4 females) with CES used PAIS bowel routine for 10 weeks.
Outcome Measures: Change in Neurogenic Bowel Dysfunction Score (NBD) over 10 weeks relative to baseline. Change in St. Mark's Fecal Incontinence score (SMFI), Cleveland Clinic Constipation score (CCC), and modified Rectal Surgeons Fecal Incontinence Quality of Life Score (QOL) at week 1, 2, 4, 6, 8 and 10 compared to baseline, and self-rating of bowel function at baseline and 10 weeks. Additionally, colonic transit times were assessed using the radioactive markers (Sitzmarks) method.
Results: Ten participants completed the study. Post-intervention primary outcome NBD score improved ( < 0.01). Secondary outcomes also improved significantly, including SMFI ( < 0.01), CCC ( < 0.01), QOL ( < 0.01), self-rating of bowel function ( < 0.01), and transit time improved by 22% ( < 0.05).
Conclusion: Overall, a significant improvement was observed with the PAIS for both primary, as well as secondary outcome measures, without any significant adverse effects. As this non-pharmaceutical method of bowel management is effective and has the potential to improve symptoms of bowel dysfunction in people with CES, it should be considered for those in which traditional methods of managing neurogenic bowel fail.
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http://dx.doi.org/10.1080/10790268.2021.2022371 | DOI Listing |
Tech Coloproctol
January 2025
Colorectal Surgery Unit, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona UAB, Barcelona, Spain.
Background: Patients with rectal cancer often experience adverse effects on urinary, sexual, and digestive functions. Despite recognised impacts and available treatments, they are not fully integrated into follow-up protocols, thereby hindering appropriate interventions. The aim of the study was to discern the activities conducted in our routine clinical practice outside of clinical trials.
View Article and Find Full Text PDFJ Pediatr Urol
December 2024
Division of Urology, Ann & Robert H. Lurie Children's Hospital of Chicago, 225 E Chicago Ave, Chicago, IL 60610, United States. Electronic address:
Background: Continent catheterizable channels (CCC) are a mainstay for reconstruction in patients with neurogenic bladders. Common complications include false passage, channel stenosis/difficult catheterization, channel incontinence, and stomal stenosis. This may result in the need for surgical revision or replacement.
View Article and Find Full Text PDFIndian J Gastroenterol
January 2025
Department of Gastroenterology, Criticare Asia Multispeciality Hospital and Research Centre, Mumbai, 400 049, India.
Gastrointestinal (GI) symptoms occur frequently in pregnant women, resulting in poor quality of life. These patients frequently require co-management with the obstetrician and a physician/GI specialist. The causation is complex and multifactorial.
View Article and Find Full Text PDFActa Gastroenterol Belg
January 2025
Gastroenterology Department, CHU Sart Tilman, Liège University, Liège, Belgium.
Background And Study Aims: Monitoring the symptoms of inflammatory bowel diseases (IBD) patients is now frequently made in the form of patient reported outcomes (PRO), rather than historical clinical activity scores. Unlike several chronic diseases, the role of telemonitoring in IBD has not yet been defined, particularly in terms of patient compliance with remote monitoring; the aim of our study was to assess patient compliance with digital monitoring of PRO as part of routine medical follow-up.
Patients And Methods: we performed a monocentric prospective study in the Gastroenterology Unit of Liège's University Hospital between May 2023 and February 2024.
Cureus
December 2024
Pediatric Medicine, Rajendra Institute of Medical Sciences, Ranchi, IND.
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