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The Attitudes Toward Polypharmacy and Willingness to Deprescribe Among Patients with Multimorbidity in Rural Areas of Shandong Province in China: A Cross-Sectional Study.

Patient Prefer Adherence

December 2024

Center for Health Management and Policy Research, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.

Purpose: Multimorbidity and polypharmacy have emerged as significant global issues, heightening the risks of potentially inappropriate medications (PIMs). This necessitates medication optimization through deprescribing. Understanding patients' decision-making preferences regarding medication cessation is crucial for mitigating medication-related risks.

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Prescribing deprescribing for polypharmacy in Aotearoa New Zealand; experiences of a medication review activity in final year medical students on a general practice module.

J Prim Health Care

December 2024

University of Otago, Wellington, Department of Primary Health Care and General Practice, Te Whare Wananga o Otago ki Te Whanga-Nui-a-Tara, 6242, New Zealand/Aotearoa.

Introduction This study explored the experiences of students and their supervisors undertaking a medication review activity during a 6-week general practice module in their final year of medical school at University of Otago, Wellington, Aotearoa New Zealand. Aim The study sought the self-reported value of the activity in learning about prescribing, reflecting on polypharmacy, deprescribing, and changes to future practice for both student and supervisor. Methods All students in the final year general practice module were invited to complete a survey over a 12-month period, as were their supervisors.

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Understanding European patterns of deprescribing antithrombotic medication during end-of-life care in patients with cancer.

Thromb Res

January 2025

Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University, Mainz, Germany; Department of Cardiology, Democritus University of Thrace, Alexandroupolis, Greece. Electronic address:

Background: Even though antithrombotic therapy (ATT) probably has little or even negative effect on the well-being of patients with cancer near the end of life, it is often continued until death, possibly leading to excess bleeding complications, increased disease burden, reduced quality of life and higher healthcare costs.

Aim: To explore and describe European practice patterns and perspectives of healthcare professionals from different disciplines and specialties on ATT in the end-of-life care (EOLC) of patients with cancer.

Methods: We performed a two-week international cross-sectional survey study using flash-mob research methodology.

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Importance: Medicare finances health care for most US patients with end-stage kidney disease (ESKD), regardless of age. Medicare enrollment may have slowed for patients with incident ESKD who gained access to new private insurance options with the 2014 passage of the Affordable Care Act (ACA) and introduction of the ACA Marketplace.

Objective: To describe trends in public and private insurance coverage and dialysis spending among patients with incident ESKD from 2012 to 2017.

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Rates and predictors of opioid deprescribing after fracture: A retrospective study of Medicare fee-for-service claims.

J Am Geriatr Soc

December 2024

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Article Synopsis
  • - The study focuses on opioid discontinuation rates and their predictors among older adults (65+) with Alzheimer's disease-related dementias (ADRD) or frailty who had undergone a fracture and started opioid treatment.
  • - It analyzed 33,027 Medicare beneficiaries and found that about 81-83% of non-frail individuals discontinued opioids within 30 days, while those with frailty or ADRD had lower discontinuation rates (76%-77%).
  • - Those with both ADRD and frailty were less likely to discontinue opioids compared to those without these conditions, indicating different opioid management needs based on health status.
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