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A new therapy for microcystic lymphatic malformations: the combination of intralesional laser thermolysis and percutaneous sclerotherapy.
Front Cell Dev Biol
December 2024
Department of Plastic Surgery, Jiangxi Provincial Children's Hospital, Nanchang, China.
Background: Over the past few decades, percutaneous sclerotherapy has been proven to be efficacy in treating macrocystic lymphatic malformations (LMs). Unfortunately, there still remains challenging in the treatment of microcystic LMs given their size. We introduce the intralesional laser thermolysis (ILT) technique, a novel enhancement technique for the traditional percutaneous sclerotherapy in the treatment of microcystic LMs.
View Article and Find Full Text PDFSupportive bandage, removable splint, or walking casts for low-risk ankle fractures in children: a feasibility randomized controlled trial.
Bone Joint J
January 2025
Musculoskeletal, Surgery, Inflammation and Recovery Theme, NIHR Biomedical Research Centre, Nottingham, UK.
Aims: It is unclear if a supportive bandage, removable splint, or walking cast offers the best outcome following low-risk ankle fractures in children. The aim of this study was to evaluate the feasibility of a randomized controlled trial to compare these treatments.
Methods: Children aged five to 15 years with low-risk ankle fractures were recruited to this feasibility trial from 1 February 2020 to 30 March 2023.
When care hurts: parents' experiences of caring for a child with epidermolysis bullosa.
Orphanet J Rare Dis
December 2024
Department of Medical Genetics, Telemark Hospital Trust, Skien, Norway.
Background: Epidermolysis bullosa (EB) comprises a group of genetically and clinically heterogeneous diseases characterized by skin fragility and blistering. EB is incurable, and treatment consists of preventing blisters in addition to painful and time consuming skin care, often performed by the parents, in addition to monitoring other symptoms in cases of severe EB.
Results: The purpose of this study was to explore parental experiences of caring for a child with EB.
Dermatopathological findings of Bothrops atrox snakebites: A case series in the Brazilian Amazon.
PLoS Negl Trop Dis
December 2024
Programa de Pós-Graduação em Medicina Tropical, Universidade do Estado do Amazonas (UEA), Manaus, Brazil.
Article Synopsis
- Bothrops snake venom causes serious local effects like pain, swelling, and bleeding; it's made up mostly of metalloproteinases and phospholipase A2 toxins.
- A study on 22 patients in Manaus highlighted common symptoms such as fang marks, infections, and blistering, along with specific skin changes like spongiosis and hyperkeratosis.
- The findings suggest that both the venom and the body’s inflammatory response contribute to skin damage, indicating a need for improved treatment strategies for snakebite victims.
Bullous Pemphigoid Onset Following Vaccination in Infancy: A Case Report.
Cureus
December 2024
Dermatology, Sheffield Children's Hospital, Sheffield, GBR.
Bullous pemphigoid (BP) is a rare autoimmune blistering disease characterised by autoantibodies against basal skin membrane antigens. Although the condition's aetiology remains unclear, recent cases have raised suspicions of an association with immunisation. In this study, we present a case of BP onset in a four-month-old infant following routine vaccination.
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