Renewed rationale for sex- and gender-disaggregated research: A COVID-19 commentary review.

Womens Health (Lond)

The George Institute for Global Health, University of New South Wales (UNSW), Newtown, NSW, Australia.

Published: February 2022

The COVID-19 pandemic provides a contemporaneous illustration of the need to consider sex and gender in research. Using surveillance, treatment and vaccine research examples, in this commentary review, we highlight opportunities for innovation in sex- and gender-sensitive and transformative health and medical research.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814978PMC
http://dx.doi.org/10.1177/17455065221076738DOI Listing

Publication Analysis

Top Keywords

commentary review
8
renewed rationale
4
rationale sex-
4
sex- gender-disaggregated
4
gender-disaggregated covid-19
4
covid-19 commentary
4
review covid-19
4
covid-19 pandemic
4
pandemic contemporaneous
4
contemporaneous illustration
4

Similar Publications

Cardiac MRI in Heart Transplantation: Approaches and Clinical Insights.

Radiographics

February 2025

From the Department of Radiology (S.Q., R.C., J.C.C., M.M., B.D.A., R.A.) and the Division of Cardiology, Department of Medicine (V.A., J.E.W., R.L.W., D.C.L.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Ste 1600, Chicago, IL 60611; Prince Charles Hospital, Chermside, Queensland, Australia (V.A.); and the Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Chicago, Ill (M.M.).

Orthotopic heart transplant (OHT) is a well-established therapy for end-stage heart failure that leads to improved long-term survival rates, with careful allograft surveillance essential for optimizing clinical outcomes after OHT. Unfortunately, complications can arise after OHT that can compromise the success of the OHT. Cardiac MRI is continually evolving, with a range of advanced techniques that can be applied to evaluate allograft structure and function.

View Article and Find Full Text PDF

This article continues from a prior commentary on evaluating the risk of bias in randomised controlled trials addressing nutritional interventions. Having provided a synopsis of the risk of bias issues, we now address how to understand trial results, including the interpretation of best estimates of effect and the corresponding precision (eg, 95% CIs), as well as the applicability of the evidence to patients based on their unique circumstances (eg, patients' values and preferences when trading off potential desirable and undesirable health outcomes and indicators (eg, cholesterol), and the potential burden and cost of an intervention). Authors can express the estimates of effect for health outcomes and indicators in relative terms (relative risks, relative risk reductions, OR or HRs)-measures that are generally consistent across populations-and absolute terms (risk differences)-measures that are more intuitive to clinicians and patients.

View Article and Find Full Text PDF

The US has an aging population that is under-represented in research. Many older adults face barriers to research participation, such as mobility issues, comorbidities, and declining physical and cognitive health, which make it harder for them to understand study processes and give informed consent. Proxies can be family members, paid or unpaid caregivers, or healthcare providers who provide health information for older adults.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!