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| http://dx.doi.org/10.1093/ehjcr/ytab522 | DOI Listing |
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Multicenter study of thermal ablation versus partial thyroidectomy for paratracheal papillary thyroid microcarcinoma.
Eur Radiol
January 2025
Department of Ultrasound, The First Medical Center, Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing, 100853, China.
Objective: To compare the clinical outcomes of patients with unifocal paratracheal papillary thyroid microcarcinoma (PTMC) after thermal ablation (TA) vs. partial thyroidectomy (PT).
Materials And Methods: This retrospective multicenter study included 436 patients with unifocal, clinical N0 paratracheal PTMC who underwent TA (210 patients) or PT (236 patients) between June 2014 and December 2020.
Spontaneously regressing mass-like soft tissue involvement in a child with chronic non-bacterial osteomyelitis: case-based review.
Rheumatol Int
January 2025
Department of Pediatric Rheumatology, Istanbul Medeniyet University, Istanbul, Turkey.
Chronic non-bacterial osteomyelitis (CNO) is an inflammatory bone disease, usually diagnosed in childhood. It is characterized by the presence of multifocal or unifocal osteolytic lesions that can cause bone pain and soft tissue swelling. CNO is known to have soft tissue involvement.
View Article and Find Full Text PDFObjective: To evaluate whether ultrasound-guided radiofrequency ablation (RFA) is reliable for unifocal T1aN0M0 papillary thyroid carcinoma in the isthmus (PTCI).
Methods: 431 patients who underwent ultrasound-guided RFA for unifocal T1aN0M0 papillary thyroid carcinoma (PTC) were divided by location of the lesion into the PTCI group (52 females, 7 males, mean age 43.79 ± 12.
Impact of thyrotropin levels on outcomes in T1N0M0 papillary thyroid cancer after microwave ablation.
Int J Hyperthermia
December 2024
Department of Interventional Medicine, China-Japan Friendship Hospital, Beijing, China.
Article Synopsis
- The study aimed to assess how different levels of thyroid-stimulating hormone (TSH) affect tumor progression and survival in patients with early-stage papillary thyroid cancer treated with microwave ablation (MWA).
- It analyzed the medical records of 525 patients, categorizing them into uni-focal (U-PTC) and multifocal (M-PTC) groups based on TSH levels after treatment, and observed the rates of tumor progression and survival outcomes.
- Results indicated that lower TSH levels in U-PTC patients correlated with higher tumor progression rates and reduced progression-free survival compared to medium and high TSH levels, whereas M-PTC patients showed no significant relationship between TSH levels and progression.
Pharmacokinetic/pharmacodynamic analysis of geographic atrophy lesion area in patients receiving pegcetacoplan treatment or sham.
CPT Pharmacometrics Syst Pharmacol
November 2024
Apellis Pharmaceuticals, Waltham, Massachusetts, USA.
Pegcetacoplan is a complement C3/C3b inhibitor indicated for the treatment of geographic atrophy (GA). A population pharmacokinetic (PK)/pharmacodynamic (PD) analysis of pegcetacoplan used GA lesion area measurements from three clinical studies to determine the effect of pegcetacoplan exposure on GA progression. A base disease progression model was developed using data from sham-treated eyes and untreated fellow eyes, followed by treatment effect assessment in dose-response and PK/PD models.
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