Transition studies have started to focus on market formation in innovation systems. This article investigates market formation in a global health transition that was instigated by drug-resistant malaria. We explore how markets for Artemisinin-based Combination Therapies (ACT) in the Greater Mekong Subregion (GMS) were formed at multiple geographical scales and locations. The study reveals the role of public institutes, academia and partnerships in early innovation system development. It demonstrates how transnational organizations created a supportive global landscape for ACT development and deployment. It then reveals how these advancements led to the formation of public-sector and private-sector ACT markets in the GMS. We illustrate how market formation activities took place on global, national and local scales and how structural couplings enabled the functioning of this global innovation system. The lessons learned are particularly relevant now that drug-resistant malaria has once more emerged in the GMS, urgently calling for new therapies and associated end-user markets.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612298 | PMC |
| http://dx.doi.org/10.1016/j.eist.2021.05.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Foliar application of sodium nitroprusside alters the physicochemical properties, antioxidant capacities, and enzymatic activities of strawberry cv. Camarosa.
Sci Rep
December 2024
Horticulture Crops Research Department, West Azerbaijan Agricultural and Natural Resources Research and Education Centre, Agricultural Research, Education and Extension Organization (AREEO), Urmia, Iran.
Strawberry (Fragaria × ananassa) is a horticultural crop known for its sensitivity to mechanical damage and susceptibility to postharvest decay. In recent years, various strategies have been implemented to enhance both the yield and quality of strawberries, among which the application of nitric oxide-producing compounds has garnered special attention. The present study aimed to investigate the effects of varying concentrations of sodium nitroprusside (SNP), specifically 0, 200, 400, and 600 μM, on strawberries (cv.
View Article and Find Full Text PDFFunctional Characterization of , a Gene Coding an Aspartic Acid Protease in .
J Fungi (Basel)
December 2024
Key Laboratory of Sustainable Crop Production in the Middle Reaches of the Yangtze River, College of Agriculture, Yangtze University, Jingzhou 434025, China.
Aspartic proteases (APs), hydrolases with aspartic acid residues as catalytic active sites, are closely associated with processes such as plant growth and development and fungal and bacterial pathogenesis. is the dominant pathogenic fungus that causes Fusarium head blight (FHB) in wheat. However, the relationship of APs to the growth, development, and pathogenesis of .
View Article and Find Full Text PDFRole of in Filamentous Growth and Pathogenicity of .
J Fungi (Basel)
November 2024
Key Laboratory of Microbiological Metrology, Measurement & Bio-Product Quality Security, State Administration for Market Regulation, College of Life Sciences, China Jiliang University, Hangzhou 310018, China.
is a dimorphic fungus that specifically infects , causing stem swelling and the formation of an edible fleshy stem known as jiaobai. The pathogenicity of is closely associated with the development of jiaobai and phenotypic differentiation. Msb2 acts as a key upstream sensor in the MAPK (mitogen-activated protein kinase) signaling pathway, playing critical roles in fungal hyphal growth, osmotic regulation, maintenance of cell wall integrity, temperature adaptation, and pathogenicity.
View Article and Find Full Text PDFStrong Heteroatomic Bond-Induced Confined Restructuring on Ir-Mn Intermetallics Enable Robust PEM Water Electrolyzers.
Angew Chem Int Ed Engl
December 2024
Huazhong University of Science and Technology, School of Chemistry and Chemical Engineering, Luoyu Road 1037, 430074, Wuhan, CHINA.
Low-iridium acid-stabilized electrocatalysts for efficient oxygen evolution reaction (OER) are crucial for the market deployment of proton exchange membrane (PEM) water electrolysis. Manipulating the in situ reconstruction of Ir-based catalysts with favorable kinetics is highly desirable but remains elusive. Herein, we propose an atomic ordering strategy to modulate the dynamic surface restructuring of catalysts to break the activity/stability trade-off.
View Article and Find Full Text PDFFeed additives for methane mitigation: Recommendations for identification and selection of bioactive compounds to develop antimethanogenic feed additives.
J Dairy Sci
January 2025
Estación Experimental del Zaidín, CSIC, 18008 Granada, Spain. Electronic address:
Despite the increasing interest in developing antimethanogenic additives to reduce enteric methane (CH) emissions and the extensive research conducted over the last decades, the global livestock industry has a very limited number of antimethanogenic feed additives (AMFA) available that can deliver substantial reduction, and they have generally not reached the market yet. This work provides technical recommendations and guidelines for conducting tests intended to screen the potential to reduce, directly or indirectly, enteric CH of compounds before they can be further assessed in in vivo conditions. The steps involved in this work cover the discovery, isolation, and identification of compounds capable of affecting CH production by rumen microbes, followed by in vitro laboratory testing of potential candidates.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!