Abnormal iron accumulation in vital organs is one of the major complications of β-thalassemia intermedia (β-TI). Silymarin, a flavonolignan isolated from , significantly decreases the serum ferritin levels of β-TI patients. This finding suggests silymarin as a safe and effective natural iron-chelating agent for the treatment of iron-overloaded conditions.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784915 | PMC |
| http://dx.doi.org/10.1002/ccr3.5293 | DOI Listing |
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