Harnessing electrical-to-biochemical conversion for microbial synthesis.

Curr Opin Biotechnol

Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA. Electronic address:

Published: June 2022

AI Article Synopsis

  • Electrical-to-biochemical conversion (E2BC) is crucial for cell metabolism and offers a green solution for biomanufacturing.
  • The review covers natural E2BC processes, artificial E2BC for microbial electrosynthesis, and innovative system designs using various technologies.
  • It also explores synthetic biology's role in enhancing microbial electrosynthesis and compares E2BC with electrocatalysis-biochemical conversion (EC2BC) for future sustainable manufacturing.

Article Abstract

Electrical-to-biochemical conversion (E2BC) drives cell metabolism for biosynthesis and has become a promising way to realize green biomanufacturing. This review discusses the following aspects: 1. the natural E2BC processes and their underlying E2BC mechanism; 2. development of artificial E2BC for tunable microbial electrosynthesis; 3. design of electrobiochemical systems using self-powered, light-assisted, and nano-biohybrid approaches; 4. synthetic biology methods for efficient microbial electrosynthesis. This review also compares E2BC with electrocatalysis-biochemical conversion (EC2BC), as both strategies may lead to future carbon negative green biomanufacturing.

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Source
http://dx.doi.org/10.1016/j.copbio.2022.102687DOI Listing

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