Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.radonc.2022.01.027 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effect of Bisphenol F on Reproductive Function in F1 Generation Male Mice and its Potential Mechanisms.
Environ Pollut
December 2024
Key Laboratory of the Provincial Education, Department of Heilongjiang for Common Animal Disease Prevention and Treatment, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China. Electronic address:
Bisphenol F (BPF) is an environmental endocrine disruptor capable of crossing the placental barrier and affecting the growth and development of offspring. Despite its potential impact, systematic research about effects of BPF on the reproductive function of male offspring remains limited. In this study, pregnant female mice were exposed to BPF at doses of 40, 400, and 4000 μg/kg during gestation and lactation, respectively, to evaluate its impact on testicular damage, testosterone levels, and spermatogenesis of male offspring (F1 generation), and further explore the mechanisms using transcriptomics.
View Article and Find Full Text PDFSaffron extract alleviates D-gal-induced late-onset hypogonadism by activating the PI3K-Akt-Nrf2 signaling pathway.
J Ethnopharmacol
December 2024
Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China; Department of Urology, Shandong Provincial Hospital, associated with Shandong University, Jinan 250021, China; College of First Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250199, China; Key Laboratory of Urinary Diseases in Universities of Shandong, Shandong First Medical University, Jinan 250021, China. Electronic address:
Ethnopharmacological Relevance: Late-onset hypogonadism (LOH) is a common age-related condition in men, characterised by a decline in serum testosterone and a range of associated signs and symptoms, and is classified as impotence in traditional medicine. Saffron is the dried stigma of Crocus sativus L., which is used in traditional medicine as an aphrodisiac.
View Article and Find Full Text PDFTestosterone promotes photoreceptor degeneration in the sodium iodate model.
Exp Eye Res
December 2024
FM Kirby Center for Molecular Ophthalmology, Scheie Eye Institute, Department of Ophthalmology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA. Electronic address:
Previously, we found that retinas of young male mice were more damaged than those of young female mice in the sodium iodate (NaIO) model. The purpose of this study was to test whether reducing testosterone levels would be retina-protective. Male C57Bl/6J mice underwent surgical castration or sham surgery, then were given an intraperitoneal injection of NaIO at 25 mg/kg.
View Article and Find Full Text PDFA Comparative Study of Equatorial and Longitudinal Incision Techniques in Micro-Dissection Sperm Extraction for Non-Obstructive Azoospermic Patients.
Urology
December 2024
Ataturk University Medical Faculty, Department of Urology, Erzurum, Turkey. Electronic address:
Objective: To compare sperm retrieval rates, postoperative pain, testicular volume, and postoperative testosterone levels between equatorial incisional microdissection testicular sperm extraction (micro-TESE) and longitidunal incisional micro-TESE in non-obstructive azoospermic (NOA) patients.
Methods: Fifty NOA patients undergoing equatorial incisional micro-TESE were retrospectively assigned to Group 1, while 50 patients undergoing longitidunal incisional micro-TESE were prospectively assigned to Group 2. Demographic data, operative time, postoperative pain assessed via the visual analog scale (VAS), complications, sperm retrieval rates, and hormonal evaluations (FSH, LH, total testosterone) were recorded.
Dietary supplementation with lycopene improves semen quality and antioxidant status in breeder roosters.
Poult Sci
December 2024
Animal Science and Technology College, Beijing University of Agriculture, Beijing 102206, PR China; Key Laboratory of Agricultural Product Processing and Quality Control (Co-construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, PR China. Electronic address:
This study investigated the effects of dietary lycopene supplementation on semen quality, testicular histology, antioxidant capacity, and reproductive hormone levels in aging breeder roosters. A total of 96 roosters were randomly divided into four groups and supplemented with 0, 50, 100, and 200 mg/kg of lycopene for six weeks. Lycopene significantly improved semen volume, sperm concentration, motility, viability, and morphological parameters at all doses (P < 0.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!