Nail psoriasis is a condition that can affect children and adolescents. It often is refractory to treatment. Data on its management in the pediatric population are limited. This article aims to summarize existing information-small case series and case reports-on the successful therapeutic approaches for nail psoriasis in children. As more agents are approved for on-label use in plaque psoriasis in pediatric patients, gradually more real-life data on their efficacy for nail psoriasis in children are expected to come to light.
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http://dx.doi.org/10.12788/cutis.0386 | DOI Listing |
Cureus
December 2024
Department of Dermatology, International University of Health and Welfare Narita Hospital, Narita, JPN.
Green nail (GN) is typically caused by and commonly occurs in patients with nail damage, nail psoriasis, or frequent exposure to moist environments. Deucravacitinib is an oral tyrosine kinase 2 (Tyk2) inhibitor effective for psoriasis treatment. Herein, we report a case of GN in a 72-year-old man following four months of treatment with deucravacitinib.
View Article and Find Full Text PDFJ Clin Med
December 2024
Department of Dermatology and Venereology, Teaching Hospital No. 2, 90-549 Lodz, Poland.
: This study is a retrospective analysis of patients with plaque psoriasis treated with biological drugs at a single center in Poland. We sought to evaluate patient demographics, disease characteristics, comorbidity burden, and treatment patterns in this cohort. : Data were collected from the medical records of patients with plaque psoriasis who received biological treatments.
View Article and Find Full Text PDFJ Clin Med
December 2024
2nd Department of Dermatology, Colentina Hospital, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Special areas of involvement in psoriasis include the scalp region, the palms and soles, genital areas, as well as intertriginous sites. The involvement of these topographical regions is associated with important physical and emotional implications, resulting in reduced quality of life, social isolation, and work disability. Palms and soles can be affected as part of the generalized form of psoriasis or can be exclusively affected as palmo-plantar psoriasis.
View Article and Find Full Text PDFJ Invest Dermatol
December 2024
Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany; Department of Dermatology, Ludwig-Maximilians University Hospital, Munich, Germany. Electronic address:
Lichen planus (LP) is a chronic inflammatory disease (ISD) affecting skin, mucosa, nail, and hair. Previous studies demonstrated a pivotal role of type 1 immunity in LP, as infiltrating T cells trigger apoptosis and necroptosis in the epidermis. In this study, we investigated the role of DAPK1 in LP with special focus on its role in mediating cell death and inflammation.
View Article and Find Full Text PDFJ Multidiscip Healthc
December 2024
Rheumatology Department, Unidade Local de Saúde de Santa Maria, Centro Académico de Medicina de Lisboa, Lisboa, Portugal.
Purpose: Psoriatic arthritis (PsA) and psoriasis (Pso) are highly heterogeneous inflammatory diseases. Multidisciplinary approaches are associated with improved results in both musculoskeletal (MSK) and skin manifestations. We describe the experience and main diagnostic and therapeutic outcomes of one of the largest and longest-running Rheumatology/Dermatology multidisciplinary PsA Clinic.
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