The COVID-19 vaccine is a scientific breakthrough to end the pandemic. We explore perceptions underlying behavioral intentions toward the COVID-19 vaccine among ultra-Orthodox Jewish males in Israel upon rollout of the vaccine. Forty-two men aged 36-56 years participated in in-depth interviews. The theoretical anchor is Miller's theory of scientific literacy. The research questions are "What perceptions shape rejection of the COVID-19 vaccine?" "What perceptions shape hesitancy and deterrence toward the COVID-19 vaccine?" and "What social forces shape behavioral intentions toward the COVID-19 vaccine?" Thematic data analysis demonstrated six themes of vaccine rejection and four themes of hesitation toward vaccination. The social forces shaping behavioral intentions are the local community's leader and the national religious authority. We highlight the need to enhance scientific literacy and reduce suspicion through collaborative community-based work among health professionals from the community, religious leaders, and lay leaders to increase acceptance of the COVID-19 vaccine.

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http://dx.doi.org/10.1177/09636625211070500DOI Listing

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