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http://dx.doi.org/10.3389/fsoc.2021.797089 | DOI Listing |
Front Immunol
March 2025
Specialised Microbiology and Laboratories, United Kingdom Health Security Agency (UKHSA), Salisbury, Wiltshire, United Kingdom.
Introduction: Nipah virus (NiV) is one of a group of highly pathogenic viruses classified within the Henipavirus genus. Since 2012 at least 11 new henipa-like viruses have been identified, including from new locations and reservoir hosts; the pathogenicity of these new viruses has yet to be determined, but two of them have been associated with morbidity, including fatalities.
Methods: The efficacy and cross-reactivity of two vaccine candidates derived from the soluble glycoproteins of both NiV and Hendra virus (HeV) was evaluated in our recently established hamster model.
Front Toxicol
February 2025
Department of Surgical Sciences, Division of Functional Pharmacology and Neuroscience, Uppsala University, Uppsala, Sweden.
Background: The specific and non-specific toxicities of cryoprotective agents (CPAs) for semen or spermatozoa cryopreservation/vitrification (SC/SV) remain challenges to the success of assisted reproductive technologies.
Objective: We searched for and integrated the physicochemical and toxicological characteristics of small-molecule CPAs as well as curated the information of all extenders reported for carnivores to provide a foundation for new research avenues and computational cryobiology.
Methods: The PubMed database was systematically searched for CPAs reported in SC/SV of carnivores from 1964 to 2024.
MRS Energy Sustain
December 2024
Department of Materials Science, University of Cambridge, Cambridge, CB3 0FS UK.
Abstract: Heating and cooling combined constitute the world's largest form of end-use energy and the largest source of carbon emissions. It is therefore interesting to explore heat pumps based on caloric materials, which offer promising and environmentally friendly alternatives to gas combustion and vapor compression. The possibility of replacing these traditional methods of heating and cooling motivates the current research on caloric materials and devices.
View Article and Find Full Text PDFFront Public Health
March 2025
National Center Rare Diseases - Undiagnosed Rare Diseases Interdepartmental Unit, Istituto Superiore di Sanità, Rome, Italy.
Background: Undiagnosed rare diseases (URDs) are a complex and multifaceted challenge, especially in low-and medium-income countries. They affect individuals with unique clinical features and lack a clear diagnostic label. Although the Undiagnosed Diseases Network International (UDNI) definition of URDs is not universally accepted, it is widely recognized.
View Article and Find Full Text PDFFront Oncol
February 2025
Biophysics Department, GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt, Germany.
Tumor motion is a major challenge for scanned ion-beam therapy. In the case of lung tumors, strong under- and overdosage can be induced due to the high density gradients between the tumor- and bone tissues compared to lung tissues. This work proposes a non-invasive concept for 4D monitoring of high density gradients in carbon ion beam therapy, by detecting charged fragments.
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