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Panretinal handheld OCT angiography for pediatric retinal imaging.
Biomed Opt Express
May 2024
Casey Eye Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Article Synopsis
- Comprehensive visualization of retina morphology is crucial for diagnosing and managing retinal diseases in children, yet conventional imaging struggles with capturing the peripheral retina effectively.
- This study introduces a novel ultra-widefield optical coherence tomography angiography (OCTA) system designed for pediatric use, featuring an ultrahigh-speed 800 kHz swept-source laser and achieving a 140° field of view with excellent optical quality.
- Over 15 months, the system has proven highly effective in diagnosing retinopathy of prematurity through detailed peripheral retinal angiography, significantly enhancing diagnostic precision and treatment customization in pediatric ophthalmology.
Optical coherence tomography (OCT) has become a key method for diagnosing and staging radiation retinopathy, based mainly on the presence of fluid in the central macula. A robust retinal layer segmentation method is required for identification of the specific layers involved in radiation-induced pathology in individual eyes over time, in order to determine damage driven by radiation injury to the microvessels and to the inner retinal neurons. Here, we utilized OCT, OCT-angiography, visual field testing, and patient-specific dosimetry models to analyze abnormal retinal layer thickening and thinning relative to microvessel density, visual function, radiation dose, and time from radiotherapy in a cross-sectional cohort of uveal melanoma patients treated with I-plaque brachytherapy.
View Article and Find Full Text PDFCase Report: Optical coherence tomography angiography findings in radiation retinopathy.
F1000Res
September 2023
Ophthalmology, University Hospital Taher Sfar, Mahdia, 5100, Tunisia.
We reported the observation of a 31-year-old female followed for a nasopharyngeal carcinoma since 2009, treated by locoregional radiotherapy, with a cumulative dose of 75 Gray. The patient presented with a progressive decline in bilateral vision. Ophthalmologic examination revealed bilateral dry eye, posterior subcapsular cataract, radiation retinopathy, and optic neuropathy.
View Article and Find Full Text PDFEffects of blue light exposure on ocular parameters and choroidal blood perfusion in Guinea pig.
Exp Eye Res
October 2023
Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, 300020, PR China; Tianjin Key Lab of Ophthalmology and Vision Science, Tianjin Eye Hospital, Tianjin, 300020, PR China; Nankai University Eye Institute, Nankai University Affiliated Eye Hospital, Nankai University, Tianjin, 300020, PR China. Electronic address:
Purpose: To investigate the impact of different duration of blue light exposure on ocular parameters and choroidal blood perfusion in guinea pigs with lens-induced myopia.
Method: Three-week-old Guinea pigs were randomly assigned to different light-environment groups. All groups were subjected to 12-h light/dark cycle.
OCTFormer: A retinal OCT-angiography vessel segmentation transformer.
Comput Methods Programs Biomed
May 2023
MIPAV Lab, the School of Electronic and Information Engineering, Soochow University, Jiangsu, China. Electronic address:
Background And Objective: Retinal vessel segmentation plays an important role in the automatic retinal disease screening and diagnosis. How to segment thin vessels and maintain the connectivity of vessels are the key challenges of the retinal vessel segmentation task. Optical coherence tomography angiography (OCTA) is a noninvasive imaging technique that can reveal high-resolution retinal vessels.
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