25-hydroxyvitamin D in older adults: Which factors really matter?

Geriatr Nurs

Departament of Medicine, Federal University of São Carlos, Rod. Washington Luís, km 235, Postal code: 13565-905 São Carlos, SP, Brazil; Graduate Program in Gerontology, Federal University of São Carlos (UFSCar), São Carlos, Brazil. Electronic address:

Published: April 2022

Background And Objectives: This study investigated the interaction between a set of factors commonly associated with vitamin D production and nutritional intake and serum 25(OH)D levels among older adults.

Methods: Cross-sectional study on 346 adults over 60 years. Serum 25(OH)D levels were measured following routine biochemical laboratory protocols. Multivariable logistic regression investigated which factors were independently associated with vitamin D deficiency.

Results: The prevalence of vitamin D deficiency and insufficiency was 35.3% and 44.2%, respectively. The multivariable logistic regression showed gender and BMI as independent adjustment measures for serum 25(OH)D levels; all other associations were non-significant.

Conclusions: Sex and BMI prevail as principal determinants of serum 25(OH)D levels among older adults. BMI seems to have a more pronounced influence on serum 25(OH)D levels of females compared to males. Healthcare professionals should consider active screening for changes in serum 25(OH)D levels in older obese adults, especially females.

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http://dx.doi.org/10.1016/j.gerinurse.2022.01.005DOI Listing

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