Purpose: To assess the reliability and validity of the Persian version of the Italian Spine Youth Quality of Life (P-ISYQOL) questionnaire.
Methods: Forward/backward translations and cultural adaption processes of the ISYQOL questionnaire into Persian were conducted by an expert committee. We recruited 178 adolescents with idiopathic scoliosis (AIS) and Scheuermann's kyphosis (SK) and 103 age-matched adolescents with no spinal deformity. Reliability was assessed by evaluating internal consistency and test-retest reliability using Cronbach's alpha and intraclass correlation coefficient (ICC). Convergent construct validity was assessed by measuring the association between the ISYQOL and revised 22-item Scoliosis Research Society (SRS-22r) questionnaires scores. Known-groups construct validity was assessed regarding curve magnitude, deformity, age, sex, and treatment type.
Results: Cronbach's alpha and ICC for P-ISYQOL total score was 0.8 and 0.9, respectively. An acceptable association was observed between P-ISYQOL and SRS-22r total scores (r = - 0.5, p < 0.01). The P-ISYQOL could discriminate between adolescents with spinal deformities and adolescents with no spinal deformity as well as those with different types of deformity and treatment (p < 0.01).
Conclusions: The P-ISYQOL is a reliable and valid survey to assess the outcomes of adolescents with spinal deformities.
Level Of Evidence: Level I-diagnostic studies.
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http://dx.doi.org/10.1007/s43390-022-00475-y | DOI Listing |
Medicina (Kaunas)
December 2024
Department of Human Neurosciences, Sapienza University of Rome, 00185 Rome, Italy.
: Musculoskeletal disorders affect a large portion of the population worldwide. The Musculoskeletal Health Questionnaire (MSK-HQ) is a helpful tool for assessing the health state of patients with these disorders. The primary goal of this study is to evaluate the psychometric properties of the MSK-HQ-IT in a population of kitesurfers.
View Article and Find Full Text PDFBrain Res Bull
December 2024
Brain Research Center, Zhongnan Hospital of Wuhan University, Wuhan, China; Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan, China. Electronic address:
Circular RNAs (circRNAs) are novel class of stable regulatory RNAs abundantly expressed in the brain. However, their role in fear extinction (EXT) memory remains largely unexplored. To investigate the mechanisms of Circular Special AT-rich Sequence Binding Protein 2 (circSatb2) in EXT memory, we constructed a lentivirus overexpressing circSatb2 and injected it into the infralimbic prefrontal cortex (ILPFC) of the mouse brain.
View Article and Find Full Text PDFEur J Phys Rehabil Med
December 2024
Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.
Nucleic Acids Res
January 2025
Bioinformatics Group, Wageningen University & Research, Droevendaalsesteeg 1, 6708 PB Wageningen, The Netherlands.
Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in agriculture, engineering and medicine. Usually, the biosynthesis of these natural products is governed by sets of co-regulated and physically clustered genes known as biosynthetic gene clusters (BGCs). To share information about BGCs in a standardized and machine-readable way, the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard and repository was initiated in 2015.
View Article and Find Full Text PDFJ Diabetes Metab Disord
December 2024
Department of Clinical and Experimental Medicine, Foggia University School of Medicine, Foggia, Italy.
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