Background: There are only few reports on ocular symptoms and manifestations in association with coronavirus disease 2019 (COVID-19).
Objective: The aim of this study is to describe ocular manifestations in the anterior and posterior segments of the eye and to analyze viral prevalence in tears of patients with COVID-19.
Methods: Hospitalized COVID-19 patients treated from 16 April 2020 to 7 January 2021 at this hospital were screened for ocular manifestations in the anterior and posterior segments. Conjunctival swabs were analyzed for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA.
Results: A total of 37 patients were enrolled in this study. In the anterior segment we found chemosis of the conjunctiva (5), hyposphagma (2) and conjunctivitis (1). In 11 patients vascular alterations and potentially disease-specific manifestations of the fundus were found in one or both eyes: retinal hemorrhages (5), cotton wool spots (5) and tortuosity (5). One patient demonstrated branch artery occlusion, one had branch retinal vein occlusion and two patients had positive conjunctival swab results in one or both eyes.
Conclusion: Our findings of the anterior segment are commonly known, although not specific for COVID-19. Various vascular fundus abnormalities were found in the study; however, it is unclear whether these were correlated to systemic comorbidities or whether they were caused or exacerbated by COVID-19. This study suggests that the risk of viral transmission via tears is low.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796747 | PMC |
| http://dx.doi.org/10.1007/s00347-022-01581-y | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Selective otolithic dysfunction in patients presenting with acute spontaneous vertigo: consideration based on MRI.
Front Neurol
December 2024
Dizziness Center, Clinical Neuroscience Center, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Objective: Acute unilateral peripheral vestibulopathy or vestibular neuritis (AUPV/VN) manifests as acute onset vertigo, often accompanied by nausea, vomiting, and moderate gait instability. It is suspected when vestibular hypofunction is documented on video-head impulse (video-HITs) and caloric tests in the presence of contralesionally beating horizontal-torsional nystagmus. Herein, we report patients presenting with acute vestibular syndrome (AVS) showing selective otolithic dysfunction in the presence of normal caloric and video-HITs and abnormal enhancement of the peripheral vestibular structures on MRI.
View Article and Find Full Text PDFAge-Related Changes in Lens Elasticity Contribute More to Accommodative Decline Than Shape Change.
Invest Ophthalmol Vis Sci
January 2025
Faculty of Health, Medicine and Social Care, Medical Technology Research Centre, Anglia Ruskin University, Bishops Hall Lane, Chelmsford, United Kingdom.
Purpose: To determine whether lens biomechanical or geometric changes contribute to the decline in the accommodative capacity of the human eye, and to examine any differences in zonular function between different age groups.
Methods: Eighteen finite element whole eye models were developed to simulate the accommodative process. Six models were constructed in each of the two age cohorts, from the fourth and the sixth decades of life using data from ex vivo human lenses.
Anderson-Fabry Disease: Focus on Ophthalmological Implications.
Life (Basel)
November 2024
Rare, Degenerative and Inflammatory Ocular Diseases Unit, Department of Sense Organs, La Sapienza University, Viale del Policlinico 155, 00161 Rome, Italy.
Fabry disease (FD) is a rare X-linked lysosomal storage disorder with a broad spectrum of clinical manifestations, including severe complications, such as end-stage renal disease, hypertrophic cardiomyopathy, and cerebrovascular disease. Enzyme replacement therapy (ERT), when initiated early, has been shown to reduce the incidence of severe events and slow disease progression. In the classic form, characterized by the absence of α-galactosidase A (α-Gal A) enzyme activity, diagnosis is straightforward.
View Article and Find Full Text PDFAdvances in Corneal Diagnostics Using Machine Learning.
Bioengineering (Basel)
November 2024
Department of Electrical & Electronic Engineering, College of Engineering, Universiti Tenaga Nasional, Kajang 43000, Malaysia.
This paper provides comprehensive insights into the cornea and its diseases, with a particular focus on keratoconus. This paper explores the cornea's function in maintaining ocular health, detailing its anatomy, pathological conditions, and the latest developments in diagnostic techniques. Keratoconus is discussed extensively, covering its subtypes, etiology, clinical manifestations, and the application of the Q-value for quantification.
View Article and Find Full Text PDFComputational Simulation of LAVA Treatment of Thyroid Eye Disease Predicts Soft Tissue Outcome Comparable to Two-Wall Resection.
Bioengineering (Basel)
November 2024
Applied Bioinformatics, German Cancer Research Center, Berliner Str. 41, 69120 Heidelberg, Germany.
Thyroid eye disease (TED) is a common extrathyroidal manifestation of hyperthyroidism, typically associated with Graves' disease (GD). This condition can cause severe functional limitations as well as significant aesthetic concerns. Treatment for TED patients aims to restore functionality and address aesthetic concerns.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!