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| http://dx.doi.org/10.4132/jptm.2021.12.29 | DOI Listing |
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University of Graz, Austria. Electronic address:
Torrey Peters' debut novel Detransition, Baby from 2021, a Women's Prize for Fiction nominee, problematizes gender norms by telling the story of three main characters: Reese, a trans woman, Ames, who de-transitioned to live as a man again, and Katrina, a Chinese and Jewish cis woman who is also Ames' lover and boss. Ames and Katrina are expecting a child and are testing the possibilities of having a non-conventional family together with Reese. Parenthood is, thus, the central theme of the novel which structures also the sections of book into the time before the conception and the weeks after it.
View Article and Find Full Text PDFAnd the story goes on: non-conventional dysplasia of the colorectum.
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Learning gain rather than learning loss during COVID-19: A proposal for reframing the narrative.
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Bloomfield College, USA.
"Learning loss" has become the new buzzword in education during the COVID-19 era. Learning loss may be real in certain academic subjects (e.g.
View Article and Find Full Text PDFTelling the same story: Fishers and landing data reveal changes in fisheries on the Southeastern Brazilian Coast.
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Departamento de Ecologia e Evolução, Marine Macroecology and Conservation Lab, Universidade Federal de Santa Maria, Bairro Camobi, Santa Maria, Rio Grande do Sul, Brazil.
An understanding of the effects of fishing on marine ecosystems relies on information about the conserved state of these environments. Non-conventional approaches such as the use of historical data and local ecological knowledge can provide information and help adjust our references of changes in the environment. Also, the combination of different types of data can indicate a fisheries trend that would be undetectable when evaluated separately.
View Article and Find Full Text PDFBeta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets.
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Institut National de la Santé et de la Recherche Médical, Unité 1151, Paris, 75015, France; Centre National de la Recherche Scientifique, UMR8253, Paris, 75015, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, 75015, France.
Research focusing on type 1 diabetes (T1D) autoantigens aims to explore our understanding of these beta cell proteins in order to design assays for monitoring the pathogenic autoimmune response, as well as safe and efficient therapies preventing or stopping it. In this review, we will discuss progress made in the last 5 years with respect to mechanistic understanding, diagnostic monitoring, and therapeutic modulation of the autoantigen-specific cellular immune response in T1D. Some technical progress in monitoring tools has been made; however, the potential of recent technologies for highly multiplexed exploration of human cellular immune responses remains to be exploited in T1D research, as it may be the key to the identification of surrogate markers of disease progression that are still wanting.
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