Presence of Microvascular Dysfunction and CHADS-VASc Score in Patients with ST-Segment Myocardial Infarction after Primary Percutaneous Coronary Intervention.

Objective: We aimed to investigate the relation between CHADS-VASc score and microvascular dysfunction (MVD) assessed by the index of microvascular resistance (IMR) immediately after primary percutaneous intervention (PPCI) for patients with ST-segment elevation myocardial infarction (STEMI).

Subjects And Methods: The study included 115 consecutive patients with STEMI who underwent successful PPCI. Angiographic results of reperfusion were inspected to evaluate the association of high CHADS-VASc score and IMR. Also, we assessed echocardiographic changes with respect to CHADS-VASc score.

Results: Subjects were stratified into 2 groups based on IMR
Conclusions: The data of the current study point out that increased CHADS-VASc score, lower systolic blood pressure <90 mm Hg, and stent diameter are associated with increased incidence of MVD (increased IMR) after PPCI of STEMI. We suggest that the CHADS-VASc score may be a simple, inexpensive useful risk score for the prediction of MVD risk after PPCI for STEMI patients.