AI Article Synopsis
- HIV infection increases the risk of developing lymphomas due to weakened immune systems and coexisting virus infections, particularly human herpesvirus 8 (HHV8).
- Co-infection with HHV8 is linked to aggressive lymphomas like primary effusion lymphoma and diffuse large B-cell lymphoma (DLBCL).
- A unique case of HHV8-positive DLBCL with significant heart involvement was found during an autopsy of a patient who had been living with untreated HIV for a long time.
Article Abstract
Human immunodeficiency virus (HIV) infection predisposes patients to the development of lymphomas, both due to immune suppression and coinfection with viruses with oncogenic potential. Coinfection with human herpesvirus 8 (HHV8) in particular has been associated with the development of aggressive lymphomas, including primary effusion lymphoma and diffuse large B-cell lymphoma (DLBCL). Herein, we report an unusual case of HHV8-positive DLBCL with extensive cardiac involvement which was diagnosed at autopsy in a patient with long-standing untreated HIV infection.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786529 | PMC |
| http://dx.doi.org/10.1155/2022/1298121 | DOI Listing |
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