To determine the impact of an adherence packaging and medication synchronization program on hospital visits for older people living independently in the community. A retrospective pre-post study that evaluated patient outcomes over a 24-month period was conducted. Patient-specific socio-demographic, medical, and hospital visit-related data were collected for 12 months before and after patient enrollment in the adherence packaging program. The study was conducted at Rx Partners LTC, LLC, a University of Pittsburgh Medical Center (UPMC) pharmacy in Pittsburgh, Pennsylvania. Patients 65 years of age or older, of any gender, with UPMC Health Plan insurance coverage, who enrolled in the adherence packaging program between July 2019 and December 2019. Enrollment in the adherence packaging program included medication synchronization and packaging in prefilled medication sets delivered to the patient's home monthly. Monthly medication reconciliation and review by clinical pharmacists was an included value-added service. Of the 92 patients included in the analysis, 60 had hospital visits during their pre-enrollment period for a total of 146 visits, compared with 54 patients in the postenrollment period totaling 126 visits; however, the mean rate of hospital visits was not statistically significant (1.59 versus 1.37; P = 0.48). Pharmacists prevented 1.87 medication errors/patient in the postenrollment setting. Enrollment in the program was associated with fewer hospital visits, though not statistically significant, and pharmacists had abundant opportunity to prevent medication errors and optimize regimens. Further evaluation is warranted in a larger cohort.
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http://dx.doi.org/10.4140/TCP.n.2022.73 | DOI Listing |
BMC Public Health
January 2025
College of Medicine and Health Sciences, Arba Minch University, P.O. Box, 21, Arba Minch City, Ethiopia.
Background: Approximately 70% of child deaths due to diarrhea are caused by a lack of timely healthcare. However, there was little evidence of factors associated with delays in seeking health care for patients with diarrheal diseases in the study area. Therefore, this study aimed to investigate delays in seeking healthcare for children with diarrhea and identify associated factors among caregivers in health centers of Northwest Ethiopia.
View Article and Find Full Text PDFEur J Pediatr
January 2025
Nutritional Epidemiology Group, School of Food Science and Nutrition, University of Leeds, Leeds, UK.
Purpose: The first 1000 days of life are critical for long-term health outcomes, and there is increasing concern about the suitability of commercial food products for infants, toddlers, and children. This study evaluates the compliance of UK commercial baby food products with WHO Nutrient and Promotion Profile Model (NPPM) guidelines.
Methods: Between February and April 2023, data on 469 baby food products marketed for infants and children under 36 months were collected from the online platforms of four major UK supermarkets.
Int J Mol Sci
December 2024
Department of Experimental Biology, Faculty of Health Sciences, University of Jaén, 23071 Jaén, Spain.
Extracellular vesicles (EVs) are a heterogeneous group of membrane-encapsulated vesicles released by cells into the extracellular space. They play a crucial role in intercellular communication by transporting bioactive molecules such as proteins, lipids, and nucleic acids. EVs can be detected in body fluids, including blood plasma, urine, saliva, amniotic fluid, breast milk, and pleural ascites.
View Article and Find Full Text PDFNeuroinformatics
January 2025
Neuro Electronics Res. Flanders (NERF), Heverlee, 3001, Belgium.
Neuropixels probes contain thousands of electrodes across one or more shanks and are sufficiently small to allow chronic recording of neural activity in freely behaving small animals. However, the joint increase in the number of electrodes and miniaturization of the probe package has led to a compromise in which groups of electrodes share a single read-out channel and only a fraction of the electrodes can be read out at any given time. Experimenters then face the challenge of selecting a subset of electrodes (i.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Public Health, Yekatit 12 Hospital Medical College, Addis Ababa, Ethiopia.
Background: In 2019, 77% of women and 82% of men with hypertension had uncontrolled hypertension worldwide. Uncontrolled hypertension can cause stroke, myocardial infarction, heart failure, renal failure, dementia, blindness, and death. However, most of the studies used the previous seventh joint national committee classification to classify hypertensive patients as either controlled or uncontrolled.
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