AI Article Synopsis

  • * A 42-year-old male with hemophilia A experienced severe chest pain and was diagnosed with an anteroseptal myocardial infarction following recent treatment with recombinant factor VIII.
  • * This case highlights the rare occurrence of acute coronary syndromes in hemophilia A patients, especially after receiving factor VIII treatment.

Article Abstract

Background: Patients with hemophilia have a hypocoagulable state and less chances of thrombus formation. Therefore, expected to have a lower cardiovascular mortality than the general population. The lower cardiovascular mortality can be explained by less chances of thrombus formation due to hypocoagulability.

Case Presentation: Here we present a case of a 42-year-old male patient presented with severe chest pain radiating to back for 4 days. ECG was suggestive of recent acute anteroseptal myocardial infarction. There was a history of receiving intravenous recombinant factor VIII, 1 hour prior to the onset of chest pain for knee joint swelling. The occurrence of acute coronary syndromes in patients with hemophilia A is uncommon and rarely reported.

Conclusion: Here we report a patient of severe hemophilia A who developed acute myocardial infarction after administration of recombinant factor VIII.

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Source
http://dx.doi.org/10.2174/1871529X22666220126122458DOI Listing

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