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Extraction and Characterization of Aceh Bovine Bone-Derived Hydroxyapatite for Applications in Dentistry.
Eur J Dent
March 2025
Department of Dental Material, Faculty of Dentistry, Universitas Syiah Kuala, Banda Aceh, Indonesia.
Objective: Bone grafts derived from natural hydroxyapatite (HA) are increasingly being explored because they are more economical in terms of production costs compared with commercial HA. HA can be obtained from local cattle slaughter waste in Aceh, Indonesia, which has not been widely studied for its potential for dental applications. This study examines the synthesis and characterization of bovine HA (BHA) derived from Aceh cattle femur through calcination for applications in dentistry.
View Article and Find Full Text PDFIs nanofat the long-awaited treatment for hypertensive ischemic leg ulcers?
Wounds
February 2025
Department of Dermatology, University Hospital of Dijon, Dijon, France.
Background: Martorell hypertensive ischemic leg ulcer (HYTILU) is a chronic, hard-to-heal wound linked to hypertension. This study explores nanofat grafting as a regenerative alternative to traditional skin grafting for improved healing and patient outcomes.
Objective: To explore the efficacy of nanofat grafting in the management of HYTILU and compare it with skin grafting.
Clinical outcomes of lyophilised human amnion/chorion membrane in treatment of hard-to-heal diabetic foot ulcers in complex cases: a case series.
J Wound Care
March 2025
MIMEDX Group, Inc., Marietta, GA, US.
Objective: Diabetic foot ulcers (DFUs) are a common and severe complication of diabetes, characterised by high morbidity, recurrence and risk of amputation. Hard-to-heal (chronic) DFUs often fail to respond to standard of care (SoC), necessitating advanced interventions. Lyophilised human amnion/chorion membrane (LHACM) is a trilayer placental allograft that provides extracellular matrix support, growth factors and anti-inflammatory properties to promote wound closure.
View Article and Find Full Text PDFLower extremity diabetic ulcers (LEDUs) are a common, high-morbidity complication of diabetes, frequently leading to infections, hospitalisations and emergency department visits. This case study examines the treatment effectiveness of a novel wound care approach in a 57-year-old female patient with a hard-to-heal LEDU (a diabetic foot ulcer of the left lower extremity) complicated by poorly controlled diabetes (glycated haemoglobin A1c: 13%). Initially, standard of care (SoC) practices, including alginate dressings, hypochlorous acid gel and sharp debridement, were ineffective in promoting significant healing.
View Article and Find Full Text PDFAdvanced progress of adipose-derived stem cells-related biomaterials in maxillofacial regeneration.
Stem Cell Res Ther
March 2025
Department of Orthodontics, School and Hospital of Stomatology, China Medical University, Nanjing North Street 117, Shenyang, 110002, China.
The tissue injury in maxillofacial region affects patients' physical function and specific mental health. This decade, utilizing regenerative medicine to achieve tissue regeneration has been proved a hopeful direction. Seed cells play a vital role in regeneration strategy.
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