Biomimetic nanotechnology relates to the most basic aspects of living systems, and the transfer of their properties to human applications [...].
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http://dx.doi.org/10.3390/biomimetics7010016 | DOI Listing |
Int J Biol Macromol
January 2025
MEMS and Nanotechnology Laboratory, School of Mechanical Engineering, Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju 61186, Republic of Korea; Advanced Medical Device Research Center for Cardiovascular Disease, Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju 61186, Republic of Korea; Center for Next-Generation Sensor Research and Development, Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju 61186, Republic of Korea. Electronic address:
Critical-sized bone defects in osteosarcoma treatment demand multifunctional scaffolds that must effectively integrate two key functions, promoting osteogenesis and delivering targeted chemoprevention. This study introduces a dual-component system featuring pH-responsive hydrogels and hydroxyapatite-based fiber-reinforced biomimetic scaffolds designed for controlled and localized curcumin delivery, while addressing its solubility and stability issues. The hydrogel system comprises a double network of polyacrylic acid, sodium alginate, carboxymethyl cellulose, and potato starch, specifically modified to encapsulate curcumin.
View Article and Find Full Text PDFBiomater Sci
January 2025
Electrochemical Process Engineering, CSIR-Central Electrochemical Research Institute (CECRI), Karaikudi-630003, Tamil Nadu, India.
Nanotechnology and 3D bioprinted scaffolds are revolutionizing the field of wound healing and skin regeneration. By facilitating proper cellular movement and providing a customizable structure that replicates the extracellular matrix, such technologies not only expedite the healing process but also ensure the seamless integration of new skin layers, enhancing tissue repair and promoting overall cell growth. This study centres on the creation and assessment of a nanostructured lipid carrier containing curcumin (CNLC), which is integrated into a 3D bioprinted PLA scaffold system.
View Article and Find Full Text PDFJ Mater Chem B
January 2025
Biomaterials Drug Delivery and Nanotechnology Unit, Centre for Biomedical and Biomaterials Research (CBBR), University of Mauritius, Réduit, Mauritius.
Tissue regeneration after a wound occurs through three main overlapping and interrelated stages namely inflammatory, proliferative, and remodelling phases, respectively. The inflammatory phase is key for successful tissue reconstruction and triggers the proliferative phase. The macrophages in the non-healing wounds remain in the inflammatory loop, but their phenotypes can be changed interactions with nanofibre-based scaffolds mimicking the organisation of the native structural support of healthy tissues.
View Article and Find Full Text PDFEnviron Res
January 2025
Marine Elements and Marine Environment Division, CSIR-Central Salt & Marine Chemicals Research Institute, Bhavnagar, 364 002, Gujarat, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. Electronic address:
Biofouling is a common phenomenon caused by waterborne organisms such as bacteria, diatoms, mussels, barnacles, algae, etc., accumulating on the surfaces of engineering structures submerged under water. This leads to corrosion of such surfaces and decreases their moving efficiency.
View Article and Find Full Text PDFBiomimetics (Basel)
January 2025
GloNeuro, Sector 107, Vishwakarma Road, Noida 201301, Uttar Pradesh, India.
Meningitis is the acute or chronic inflammation of the protective membranes, surrounding the brain and spinal cord, and this inflammatory process spreads throughout the subarachnoid space. The traditional drug delivery methods pose a disadvantage in limiting the capacity of crossing the blood-brain barrier (BBB) to reach the central nervous system (CNS). Hence, it is imperative to develop novel approaches that can overcome these constraints and offer efficient therapy for meningitis.
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