Upper gastrointestinal (GI) bleeding is a common presentation in emergency departments (EDs). This medical emergency has a mortality rate of up to 14%, particularly in men and older people. The most frequent cause of upper GI bleeding is peptic ulcer disease. Management has not changed significantly in the past 50 years and there is ongoing debate in the literature about the most effective treatment protocols. This article uses a case study of a patient who presented to an ED with upper GI bleeding caused by peptic ulcer disease to examine the evidence on treatment and management. The article also discusses a care bundle that has been developed for rapid assessment and management of patients with acute upper GI bleeding.

Download full-text PDF

Source
http://dx.doi.org/10.7748/en.2022.e2120DOI Listing

Publication Analysis

Top Keywords

upper bleeding
12
upper gastrointestinal
8
gastrointestinal bleeding
8
peptic ulcer
8
ulcer disease
8
upper
5
bleeding
5
managing patient
4
patient presenting
4
presenting emergency
4

Similar Publications

Background Endoscopic dilatation is the cornerstone therapy for esophageal strictures. The primary indication for dilatation is to provide immediate and durable symptomatic relief from dysphagia. Following esophageal dilatation, the two most common major consequences are bleeding and perforation, both of which are quite rare.

View Article and Find Full Text PDF

Positive drain fluid culture on postoperative day one is associated with an increased risk of late postoperative pancreatic fistula after pancreaticoduodenectomy.

Langenbecks Arch Surg

January 2025

Hepatopancreatobiliary Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.

Purpose: To investigate the risk factors for late postoperative pancreatic fistula (POPF) following pancreaticoduodenectomy (PD), with a focus on positive drain fluid culture (DFC) results on postoperative day (POD) 1.

Methods: Medical records of 198 patients who underwent PD with drain fluid amylase (DFA) on POD 5 < 3x upper limit of normal (ULN) were included. Late POPF was defined as POPF diagnosed post-POD 6, with DFA on POD 5 < 3xULN.

View Article and Find Full Text PDF

Background: Tooth agenesis, particularly the absence of upper lateral incisors, presents substantial challenges for clinicians due to the associated bone atrophy, which limits the use of traditional implant solutions. Current options, such as endosseous implants combined with guided bone regeneration (GBR), often fail due to insufficient osseointegration in atrophic bone. This study aims to evaluate the effectiveness of custom-made, additively manufactured subperiosteal implants in addressing these challenges METHODS: This retrospective study assessed 16 custom-made subperiosteal implants used in 12 patients (10 females, 2 males; mean age 25 ± 2.

View Article and Find Full Text PDF

Caesarean myomectomy in pregnant women with uterine fibroids.

Cochrane Database Syst Rev

January 2025

Liverpool Reviews and Implementation Group, Department of Health Data Science, University of Liverpool, Liverpool, UK.

Rationale: Postpartum haemorrhage, defined as a blood loss of 500 mL or more within 24 hours of birth, is the leading global cause of maternal morbidity and mortality. Uterine fibroids are non-cancerous growths that develop in or around the uterus, and affect an increasing number of women. Caesarean myomectomy is the surgical removal of fibroids during a caesarean section.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!