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| http://dx.doi.org/10.4103/jpgm.jpgm_391_21 | DOI Listing |
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Recurrent Diffuse Tenosynovial Giant Cell Tumor of the Temporomandibular Joint.
Head Neck Pathol
January 2025
Department of Pathology and Laboratory Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Purpose: Recurrent diffuse-type tenosynovial giant cell tumor: Clinical presentation, Diagnosis, and Management.
Background: Tenosynovial giant cell tumor (TGCT), is a neoplasm arising from synovial joints, bursae, or tendon sheaths. The initial clinical symptoms are vague and non-diagnostic.
Is calcification integral to enthesopathy and tendinopathy rather than a separate disease process?
J Orthop
July 2025
Department of Surgery and Perioperative Care, Dell Medical School-The University of Texas at Austin, Austin, TX, USA.
Background: The pathophysiology of enthesopathy and tendinopathy is mucoid degeneration, which includes chondroid metaplasia. The chondroid metaplasia can be associated with calcification. Inflammation is typically absent unless calcification triggers a self-limited immune response representing acute calcific tendinitis.
View Article and Find Full Text PDFArticle Synopsis
- A chondroid syringoma is a rare, non-cancerous skin tumor that can have unique characteristics in its tissue makeup, sometimes causing confusion during diagnosis.
- This report details a case involving this tumor, with unusual bone formation, located on the right upper eyelid of a 60-year-old woman.
- The patient's tumor showed low levels of cell proliferation (Ki67 index) and after a 36-month follow-up, there was no sign of the tumor returning, highlighting the importance of recognizing this tumor's varied appearances to avoid misdiagnosis.
Exploring the molecular landscape of cutaneous mixed tumors characterized by TRPS1::PLAG1 gene fusion.
J Pathol
December 2024
Department of Pathology, Institute de Pathologie Multisite, Groupement Hospitalier Sud, Lyon University Hospital, Pierre-Bénite, France.
The histological similarities between pleomorphic adenomas (PAs) and cutaneous mixed tumors (CMTs) found in certain facial regions can create a diagnostic challenge. Molecular findings reveal common genetic profiles, particularly PLAG1 rearrangements in both PA and CMT. Although molecular distinctions have received limited attention, our observations indicate multiple cases of CMTs carrying the TRPS1::PLAG1 fusion.
View Article and Find Full Text PDFDistribution of mechanical properties of native human ligamentum flavum depending on histopathological changes.
Biomed Phys Eng Express
September 2024
Faculty of Mechanical Engineering, Czech Technical University in Prague, Technicka 4, 16607 Prague, Czech Republic.
This study aimed to characterize the mechanical properties of native human ligamentum flavum (LF) and correlate them with histopathological changes. Mechanical property gradients across the cranial, medial, and caudal regions of LF were mapped and compared with histological sections. We also compared lumbar spinal stenosis (LSS) samples with disc herniation (DH) samples as reference material to identify differences in mechanical properties and histopathological features.
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