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A sinonasal yolk sac tumor in an adult. | LitMetric

A sinonasal yolk sac tumor in an adult.

J Pathol Transl Med

Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Published: May 2022

Yolk sac tumors (YSTs), which are also called endodermal sinus tumors, are malignant tumors of germ cell origin. These tumors usually occur in the gonads, but 20% of cases have been reported at extragonadal sites. The head and neck is a rarely affected region that accounts for just 1% of all malignant tumors of germ cell origin. In addition, YSTs arise mostly in childhood. We present a rare pathologically pure case of primary adult YST in the sinonasal area. A 45-year-old male patient presented with a rapidly growing mass in the nasal cavity, which caused nasal obstruction and bloody post-nasal drip. The histopathologic features indicated pure YST, and immunohistochemical analysis revealed positive reactivity for Sal-like protein 4 and alpha-fetoprotein. Herein, we discuss the clinical, radiologic, and histologic features of this YST and review other cases of sinonasal YST in adults.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119804PMC
http://dx.doi.org/10.4132/jptm.2021.12.09DOI Listing

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