AI Article Synopsis
- COVID-19 affects not only the respiratory system but also causes severe complications like gastrointestinal issues, kidney injury, and cardiovascular problems, including thrombosis.
- Natural products have shown potential in alleviating COVID-19 symptoms and improving immune response, making them an accessible option for management.
- The study employs network pharmacology to explore the therapeutic benefits of these natural products against COVID-19-related thrombosis and their influence on immune responses.
Article Abstract
Coronavirus disease 2019 (COVID-19) not only targets the respiratory system but also triggers a cytokine storm and a series of complications, such as gastrointestinal problems, acute kidney injury, and myocardial ischemia. The use of natural products has been utilized to ease the symptoms of COVID-19, and in some cases, to strengthen the immune system against COVID-19. Natural products are readily available and have been regularly consumed for various health benefits. COVID-19 has been reported to be associated with the risk of thromboembolism and deep vein thrombosis. These thrombotic complications often affects mortality and morbidity. , which has been widely consumed for its various health benefits has also been reported for its therapeutic effects against cardiovascular disease, thrombosis and platelet aggregation. In this review, we propose that can be consumed as a supplementation against the various associated complications of COVID-19, especially against thrombosis. We utilized the network pharmacology approach to validate the potential therapeutic properties of against COVID-19 mediated thrombosis, the coagulation pathway and platelet aggregation. Additionally, we aimed to investigate the roles of against COVID-19 with the involvement of platelet-leukocyte aggregates in relation to immunity-related responses in COVID-19.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767971 | PMC |
| http://dx.doi.org/10.1016/j.jgr.2022.01.002 | DOI Listing |
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