Plasmid Carrying , , and Genes in From Regional Hospital in Mexico.

Introduction: is an opportunistic bacteria that have been recognized as significant pathogens in patients with underlying diseases or immunocompromised status. The aim of this study was to identify extended-spectrum β-lactamases in clinical isolates of

Methods: This cross-sectional study was conducted at Hospital Central "Dr. Ignacio Morones Prieto" in San Luis Potosi, Mexico. Nineteen isolates of were obtained from clinical specimens between April to December 2015. Four isolates were resistant to third-generation cephalosporins. The presence of genes encoding ESBL ( , , , , and ) was analyzed by PCR. For this purpose, plasmid DNA was extracted and horizontally transferred to recipient Top 10.

Results: and genes were detected in and , whereas gene was identified in 1 isolate of In contrast, gene was not detected in any isolate. One strain carried , , , and genes, most in a 275-kb plasmid.

Conclusion: This study shows the presence of different types of ESBL in clinical isolates of and , which confer resistance to broad-spectrum β-lactams. The plasmid identified in this study harboring ESBL genes could play an important role in the dissemination of antibiotic resistance.