Idiopathic granulomatous mastitis and steroid use during the pandemic of COVID-19.
Breast Dis
Department of General Surgery, Faculty of Medicine, Alanya Alaaddin Keykubat University, Alanya, Turkey.
Published: January 2022
Background: Steroid therapy is an immunosuppressive treatment and may have possible side effects in a pandemic period. However, the number of studies on the use corticosteroids for the treatment of idiopathic Granulomatous Mastitis (IGM) especially during the pandemic is almost negligible.
Methods: The data of patients with the diagnosis of IGM between January-December 2020 in the General Surgery Clinic were retrospectively analyzed. The patients were explained in detail that steroid therapy is an immunosuppressive treatment and it may have possible side effects. Prednisolone 0.5-1 mg/kg/day was given as steroid therapy. The treatment was planned for 4-6 months according to the severity of the symptoms and was completed by reducing it to a total dose of 10 mg/month.
Results: Eleven patients were included in the study. Five patients had completed steroid treatment and continued their follow-up. In our study, a total of six patients were receiving steroid therapy.
Conclusions: There is no consensus yet on the use of the steroid in the COVID-19 pandemic. Low doses Corticosteroids (<1 mg/kg/day) don't have an effect on increase mortality in patients with severe COVID-19. We can think that low-dose corticosteroids used by many centers in IGM treatment do not have a negative effect on mortality.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3233/BD-210054 | DOI Listing |
Similar Publications
Inhibiting EZH2 complements steroid effects in Duchenne muscular dystrophy.
Sci Adv
March 2025
Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.
Duchenne muscular dystrophy (DMD) is a devastating X-linked disorder caused by dystrophin gene mutations. Despite recent advances in understanding the disease etiology and applying emerging treatment methodologies, glucocorticoid derivatives remain the only general therapeutic option that can slow disease development. However, the precise molecular mechanism of glucocorticoid action remains unclear, and there is still need for additional remedies to complement the treatment.
View Article and Find Full Text PDFDacryoendoscopy in patients with lacrimal outflow obstruction: a systematic review.
Int Ophthalmol
March 2025
Department of Ophthalmology and Visual Sciences, Faculty of Medicine, The Chinese University of Hong Kong, 4/F, Hong Kong Eye Hospital, 147K Argyle Street, Kowloon, Hong Kong Special Administrative Region, China.
Purpose: Dacryoendoscopy (DE) is an emerging, minimally invasive, surgical technique for lacrimal outflow obstruction (LOO). This is a systematic review on the diagnostic and therapeutic use, as well as the safety of DE in the lacrimal literature.
Methods: Up to 22nd November, 2024, 259 studies were retrieved from PubMed, Cochrane Library, and Ovid MEDLINE.
A case report on 'fortuitous diagnosis of ocular cysticercosis in a case of unrelated eye injury'.
Int Ophthalmol
March 2025
Department of Optometry, School of Allied Health Sciences, Galgotias University, Greater Noida, India.
Introduction: Cysticercosis, a parasitic infection caused by Taenia solium, is often contracted through the consumption of contaminated undercooked vegetables, pork, or beef. Ocular involvement, although rare, can have severe consequences if untreated. This case report highlights the importance of prompt diagnosis and treatment of ocular cysticercosis.
View Article and Find Full Text PDFUnveiling the superiority: single catheter multisite epidural blood patch for the treatment of spontaneous intracranial hypotension.
Neurosurg Rev
March 2025
Department of Anaesthesia and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Spontaneous intracranial hypotension (SIH) is a rare clinical condition that may occur due to cerebrospinal fluid leakage. The purpose of this study was to compare the safety and efficacy of single catheter multisite epidural blood patch(CA-EBP) with standard procedures, including blinded and targeted epidural blood patch (EBP) for the treatment of SIH, and to investigate the effectiveness of dexamethasone as an adjuvant. Clinical data of 68 patients with postoperative SIH who underwent EBP between March 2022 and May 2024.
View Article and Find Full Text PDFTherapy Dogs for Anxiety in Children in the Emergency Department: A Randomized Clinical Trial.
JAMA Netw Open
March 2025
Department of Emergency Medicine, Wayne State University School of Medicine, Detroit, Michigan.
Importance: Prior evidence suggests that the use of therapy dogs in emergency care reduces anxiety in adults, but no trial has tested the use of therapy dogs in emergency care of children.
Objective: To examine whether adjunctive use of therapy dogs in standard child-life therapy reduces child-reported and parent-reported child anxiety in a pediatric emergency department (ED).
Design, Setting, And Participants: This randomized clinical trial was conducted from February 1, 2023, to June 30, 2024, at an academic pediatric ED.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!
© LitMetric 2025. All rights reserved.