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Vitamin D status and its determinants in German elite athletes.
Eur J Appl Physiol
January 2025
Department of Exercise Physiology and Sports Therapy, Institute of Sports Science, Justus Liebig University Giessen, Kugelberg 62, 35394, Giessen, Germany.
Purpose: This study investigated elite German athletes to (1) assess their serum 25(OH)D levels and the prevalence of insufficiency, (2) identify key factors influencing serum 25(OH)D levels, and (3) analyze the association between serum 25(OH)D levels and handgrip strength.
Methods: In this cross-sectional study, a total of 474 athletes (231 female), aged 13-39 years (mean 19.3 years), from ten Olympic disciplines were included.
Increased hip fracture risk in the patients with type 2 diabetes mellitus is correlated with urine albumin-to-creatinine ratio (ACR) and diabetes duration in men.
Exp Biol Med (Maywood)
December 2024
Department of Endocrinology, Shanghai Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.
Patients with type 2 diabetes mellitus (T2DM) have increased hip fracture risk. And the association between urine albumin to creatinine ratio (ACR) and an increased risk of hip fracture in patients with T2DM remains controversial. This study aimed to investigate the association between urinary ACR and hip fracture risk in postmenopausal women and aged men with T2DM.
View Article and Find Full Text PDFCausal Relationships Between Epilepsy, Anti-Epileptic Drugs, and Serum Vitamin D and Vitamin D Binding Protein: A Bidirectional and Drug Target Mendelian Randomization Study.
CNS Neurosci Ther
December 2024
Department of Neurosurgery, SanBo Brain Hospital, Capital Medical University, Beijing, China.
Aims: Previous studies suggest potential associations between epilepsy, anti-epileptic drugs (AEDs), and levels of vitamin D and vitamin D-binding protein (VDBP). This study aims to investigate the causal relationships among these variables using Mendelian Randomization (MR) methods.
Methods: Using summary data from genome-wide association studies on serum 25-hydroxyvitamin D [25(OH)D] levels (N = 417,580), VDBP concentrations (N = 65,589), and various types of epilepsy (Ncases = 27,559), MR analyses were conducted to determine bidirectional causal relationships among these variables.
Characteristics of lipid metabolism and fat distribution in patients with primary hyperparathyroidism and their Mendelian randomization study.
Endocrine
December 2024
Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Article Synopsis
- The study investigates the relationship between primary hyperparathyroidism (PHPT) and lipid metabolism, analyzing clinical data and fat distribution in 157 PHPT patients compared to matched controls.
- Previous research hints at a link between parathyroid hormone (PTH) levels and lipid profiles, yet this study finds no significant differences in lipid-related measurements or fat distribution between PHPT patients and controls.
- Overall, the analysis suggests that PTH levels do not have a significant impact on lipid metabolism indicators, as various correlations remained non-significant even after accounting for factors like calcium levels and vitamin D.
Vitamin D status in patients with chronic obstructive pulmonary disease at Chris Hani Baragwanath Hospital, Johannesburg, South Africa.
Afr J Thorac Crit Care Med
October 2024
Division of Critical Care, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand and Chris Hani Baragwanath Academic Hospital, Johannesburg, South Africa.
Article Synopsis
- A study in Johannesburg, South Africa, examined vitamin D levels in 76 COPD patients, focusing on deficiency (≤20 ng/mL) and insufficiency (21-29 ng/mL).
- Findings revealed that 48% of patients were vitamin D deficient and 35% were insufficient, with sunlight exposure being a key factor in deficiency risk.
- The results indicate significant suboptimal vitamin D levels in this demographic, highlighting a need for further research, especially in African populations.
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