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Cortical hemodynamics of electrographic status epilepticus in the critically ill.
Epilepsia
December 2024
Department of Neurosciences, Université de Montréal, Montréal, Québec, Canada.
Objectives: The pathophysiological mechanisms of status epilepticus (SE) underlying potential brain injury remain largely unclear. This study aims to employ functional near-infrared spectroscopy (fNIRS) combined with video-electroencephalography (vEEG) to monitor brain hemodynamics continuously and non-invasively in critically ill adult patients experiencing electrographic SE. Our primary focus is to investigate neurovascular coupling and cerebrovascular changes associated with seizures, particularly during recurring and/or prolonged episodes.
View Article and Find Full Text PDFIdentification of Potential Genes in Rheumatoid Arthritis-Associated Interstitial Lung Disease Using RNA-seq and In Vitro Analyses.
Cell Biochem Funct
January 2025
Department of Rheumatology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is an increasingly recognized extra-articular manifestations (EAMs) in the RA, with highly morbidity and mortality. The identification of key molecules involved in RA-ILD has a high requirement in clinic, and the role of their transcriptional regulation in the etiology of RA-ILD is great significant for investigation. In this study, we collected the whole peripheral blood samples of RA-ILD and RA only patients to bulk RNA-sequence.
View Article and Find Full Text PDFNitrous oxide (NO) is generally used in the medical and food industries. However, it is sometimes illegally misused by young adults as a recreational drug. In either of these uses, functional vitamin B12 deficiency results in neurological implications, such as peripheral neuropathy and subacute combined degeneration (SACD).
View Article and Find Full Text PDFA study of SGLT2 inhibitors on levels of plasma atherogenesis biomarkers in diabetes.
J Family Med Prim Care
November 2024
Resident Internal Medicine, Madras Medical College, Chennai, Tamil Nadu, India.
Background: Diabetes, a chronic metabolic disorder with microvascular and macrovascular complications. Metabolites of hyperglycemia mediates endothelial injury resulting in cascade of atherosclerosis. Atherosclerosis sets up plaque in vessel wall and obliterates the vascular lumen which results in stroke, myocardial infarction, and peripheral vascular disease.
View Article and Find Full Text PDF[Characteristics and Influencing Factors of Soil Particulate and Mineral-associated Organic Carbon in Cropland Soil across Sichuan Basin].
Huan Jing Ke Xue
January 2025
College of Resources, Sichuan Agricultural University, Chengdu 611130, China.
Exploring the composition of regional soil organic carbon （SOC） components and identifying their influencing factors are of utmost importance to deeply understand the potential mechanisms of SOC change in cropland soil. Based on data from 871 soil sampling points, this study explored the characteristics of soil particulate and mineral-associated organic carbon （POC and MAOC） in the surface soil of cropland and the relationships with climate, terrain, soil texture, agricultural land-use type, and fertilization across the Sichuan basin using analysis of variance, correlation analysis, and a random forest model. The results showed that the average content of POC and MAOC in the surface soil of cropland was 5.
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