Dermoscopic images are commonly used in the early diagnosis of skin lesions, and several computational systems have been proposed to analyze them. The segmentation of the lesions is a fundamental step in many of these systems. Therefore, a semi-automatic segmentation method is proposed here, which begins by building the superpixels of the image under analysis based on the zero parameter version of the simple linear iterative clustering (SLIC0) algorithm. Then, each superpixel is represented using a descriptor built by combining the grey-level co-occurrence matrix and Tamura texture features. Afterward, the gain ratios of the features are used to select the input for the semi-supervised seeded fuzzy C-means clustering algorithm. Hence, from a few specialist-selected superpixels, this clustering algorithm groups the built superpixels into lesion or background regions. Finally, the segmented image undergoes a post-processing step to eliminate sharp edges. The experiments were performed on 1380 images: 401 images from the PH and DermIS datasets, which were used to establish the parameters of the method, and 3,573 images from the ISIC 2016, ISIC 2017 and ISIC 2018 datasets were used for the analysis of the method's performance. The findings suggest that, by manually identifying just a few of the generated superpixels, the method can achieve an average segmentation accuracy of 96.78%, which confirms its superiority to the ones in the literature.
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http://dx.doi.org/10.1016/j.media.2022.102363 | DOI Listing |
Sci Rep
January 2025
Institute for X-ray Physics, Georg-August University Göttingen, Friedrich-Hund-Platz 1, 37077, Göttingen, Germany.
Imaging the entire cardiomyocyte network in entire small animal hearts at single cell resolution is a formidable challenge. Optical microscopy provides sufficient contrast and resolution in 2d, however fails to deliver non-destructive 3d reconstructions with isotropic resolution. It requires several invasive preparation steps, which introduce structural artefacts, namely dehydration, physical slicing and staining, or for the case of light sheet microscopy also clearing of the tissue.
View Article and Find Full Text PDFFront Neurol
January 2025
Department of Neurology, Ajou University School of Medicine, Suwon, Republic of Korea.
Background: This study aims to investigate how A1 segment asymmetry-also known as A1 dominancy-influences the development of the anterior communicating artery aneurysm (AcomA) as it affects hemodynamic conditions within the circle of Willis (COW). Using time-of-flight magnetic resonance angiography (TOF-MRA), the research introduces a novel approach to assessing shear stress in A1 segments to uncover the hemodynamic factors contributing to AcomA formation.
Method: An observational study was conducted over 6 years at a tertiary university hospital's outpatient clinic.
Front Neurol
January 2025
Department of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Objective: To develop a machine learning-based clinical and/or radiomics model for predicting the primary site of brain metastases using multiparametric magnetic resonance imaging (MRI).
Materials And Methods: A total of 202 patients (87 males, 115 females) with 439 brain metastases were retrospectively included, divided into training sets (brain metastases of lung cancer [BMLC] = 194, brain metastases of breast cancer [BMBC] = 108, brain metastases of gastrointestinal tumor [BMGiT] = 48) and test sets (BMLC = 50, BMBC = 27, BMGiT = 12). A total of 3,404 quantitative image features were obtained through semi-automatic segmentation from MRI images (T1WI, T2WI, FLAIR, and T1-CE).
Laryngoscope Investig Otolaryngol
February 2025
Objective: The primary aim of this study was to investigate the accuracy of a semi-automatic algorithm in assessing the feasibility and complexity of endoscopic stapes surgery preoperatively.
Methods: A semi-automatic algorithm was developed to simulate endoscopic stapes surgery in 3D. To test the accuracy of the algorithm, five fresh-frozen cadaveric heads (ten ears) were used.
J Inflamm Res
January 2025
Department of Radiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, People's Republic of China.
Background: Accurately assessing the activity of Crohn's disease (CD) is crucial for determining prognosis and guiding treatment strategies for CD patients.
Objective: This study aimed to develop and validate a nomogram for assessing CD activity.
Methods: The semi-automatic segmentation method and PyRadiomics software were employed to segment and extract radiomics features from the spectral CT enterography images of lesions in 107 CD patients.
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