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A biomimetic sperm selection device for routine sperm selection.
Reprod Biomed Online
September 2024
University of Technology Sydney, Sydney, Australia; Institute for Biomedical Materials and Devices, University of Technology Sydney, Sydney, Australia. Electronic address:
Research Question: Can a biomimetic microfluidic sperm sorter isolate motile sperm while minimizing DNA damage in comparison with density gradient centrifugation (DGC)?
Design: This was a two-phase study of 61 men, consisting of a proof-of-concept study with 21 donated semen samples in a university research laboratory, followed by a diagnostic andrology study with 40 consenting patients who presented at a fertility clinic for semen diagnostics. Each sample was split to perform DGC and microfluidic sperm selection (one-step sperm selection with 15 min of incubation) side-by-side. Outcomes evaluated included concentration, progressive motility, and DNA fragmentation index (DFI) of raw semen, and sperm isolated using DGC and the microfluidic device.
Genetic study on candidates for oocyte donation.
JBRA Assist Reprod
December 2024
Genetics Unit, Department of Pathology, University of Porto, Alameda Professor Hernâni Monteiro, 4200-319, Porto, Portugal.
Objective: There is a rising demand for assisted reproductive medicine, including sperm, oocyte and embryo donation. Besides medical and legal considerations, genetic testing, including carrier screening for multiple autosomal and X-linked recessive disorders plays an essential role in evaluating hereditary risk among donors and therefore exclude them from the donation process.
Methods: A retrospective study was conducted on oocyte donors from a private clinic of assisted reproduction who underwent genetic testing between June 2014 and September 2023.
The Probiotics , , and Enhance Spermatozoa Motility Through Mitochondrial Function-Related Factors.
Int J Mol Sci
December 2024
Department of Biomedical Science, College of Life Science, CHA University, Pocheon 11160, Gyeonggi-do, Republic of Korea.
Idiopathic male infertility is characterized by increased mortality or reduced motility and vitality of sperm. There are several reports on probiotics in the male reproductive tract, but the effects of these probiotics on sperm motility remain to be elucidated. In this study, we investigated the impact and mechanism of probiotics on the vitality and motility of mouse sperm.
View Article and Find Full Text PDFThe emotions, concerns and reactions of sperm donor candidates to their rejection by a sperm bank.
J Assist Reprod Genet
December 2024
Cryos International, Vesterbro Torv 3, 8000, Aarhus C, Denmark.
Purpose: To explore the emotions, concerns and reactions of sperm donor candidates to their rejection by the sperm bank.
Methods: An online questionnaire was administered at Cryos International in the USA and Denmark to sperm donor candidates who had received notification that they were ineligible to donate.
Results: A total of 101 rejected donor candidates completed the questionnaire.
Stringent Regulations of Oocyte Donation Among Jewish Women in Israel: Characteristics and Outcomes of the National Oocyte Donation Program in One Central IVF Unit.
J Relig Health
December 2024
Racine IVF Unit, Affiliated to the Sackler Faculty of Medicine, Tel Aviv Sourasky Medical Center, Fertility Institute, Lis Maternity Hospital, Tel Aviv University, 6 Weizmann Street, Tel Aviv, Israel.
On September 5, 2010, the Israeli Parliament passed a law that allows Israeli female residents to donate their oocytes to infertile Israeli female residents. This law includes unique restrictions that do not exist in other countries. Our aim was to characterize Israeli oocyte donors and recipients and the outcomes of the oocyte donation program as regulated by national law.
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