Aim: To search feasibility and reliability of Telemedicine Systems (TS) in the remote multidisciplinary oncology conference for decision making and treatment of liver lesions.
Material And Methods: By an experimental TS, twenty six (n=26) specialists based on a series of five (N=5) simulated remote image examinations, assessed sensitivity-specificity of the remote examination of the Liver (L) for neoplastic diseases and damages (Virtual Examination=VE).
Results: Analysis showed injuries (sensitivity=96%), injuries of the capsula (sensitivity=91.7%), hematomas (sensitivity=91,7%), non-neoplastic diseases (specificity=100%), neoplastic diseases (sensitivity=100%).
Conclusion: The VE of the (L) in combination with high-tech visualization and multimedia and the remote participation of liver surgical oncology, oncology, radiology, pathology and cytology experts composes a feasible and reliable e-Multidisciplinary Oncologic Conference for a Personalized and Optimum Decision Making and Treatment in Liver Cancer.
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http://dx.doi.org/10.3233/SHTI210922 | DOI Listing |
Metastasis stands as one of the most prominent prognostic factors in osteosarcoma. Over 70% of metastatic osteosarcoma occurrences affect the lung. Nonetheless, to date, there has been a scarcity of research addressing predictive factors for lung metastasis risk in osteosarcoma.
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Liverpool Reviews and Implementation Group, Department of Health Data Science, University of Liverpool, Liverpool, UK.
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National Center for Cancer Immune Therapy, Department of Oncology, Copenhagen University Hospital, Herlev, Denmark. Electronic address:
Groundbreaking studies have reshaped the treatment landscape for patients with resectable stage ≥IIIB melanoma by demonstrating the benefits of neoadjuvant therapy. Data from the NADINA and SWOG S1801 trials reveal substantial improvements in event-free survival compared to adjuvant therapy alone. These studies employed distinct neoadjuvant immunotherapy approaches - ipilimumab plus nivolumab in NADINA and anti-PD-1 monotherapy in SWOG S1801 - highlighting potential differences in efficacy and toxicity.
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January 2025
Unit of Gynecology and Obstetrics, Department of Women and Children's Health, University of Padua, 35122 Padua, Italy.
Cancer immunotherapy through the use of PD-1/PD-L1 inhibitors have shown significant promise in endometrial carcinoma (EC), particularly in tumors with microsatellite instability (MSI) or mismatch repair deficiency (dMMR), present in approximately 30% of cases. This review evaluated PD-L1 and PD-1 expression as potential biomarkers for immunotherapy response in EC, focusing on their relationship with MSI status. A systematic review, adhering to PRISMA guidelines, analyzed studies from MEDLINE and Embase until February 2023 on PD-1/PD-L1 expression in EC stratified by MSI status, including diverse study designs but excluding conference abstracts, with independent screening, data extraction, and additional reference checks to ensure comprehensive coverage.
View Article and Find Full Text PDFChildren (Basel)
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Department of Pediatric and Adolescent Surgery, Medical University of Graz, 8036 Graz, Austria.
: Advancements in artificial intelligence (AI) and machine learning (ML) are set to revolutionize healthcare, particularly in fields like endoscopic surgery that heavily rely on digital imaging. However, to effectively integrate these technologies and drive future innovations, pediatric surgeons need specialized AI/ML skills. This survey evaluated the current level of readiness and educational needs regarding AI/ML among members of the European Society of Pediatric Endoscopic Surgeons (ESPES).
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