AI Article Synopsis
- Cationic complex coacervates can be used in medical applications to control how substances are delivered or released.
- A specific type of poly(allylamine hydrochloride) and phosphate were used to create a coacervate that allows for a controlled release of phosphate, important for mineralization processes.
- These coacervates have beneficial properties like high wettability and moldability, making them suitable as a new form of hydrogels for mineralizing calcium phosphate in dental and bone applications.
Article Abstract
Cationic complex coacervates are contemplated for various medical applications controlling carrier or release processes. Here, lower poly(allylamine hydrochloride) (15 kg/mol) and (hydrogen)phosphate as cross-linking units were chosen to facilitate a sufficient coacervation and subsequently a controllable phosphate release, essential for consecutive mineralization reactions. In addition, the rheological characteristics of the obtained coacervates were assessed, exhibiting a pronounced liquid character, which enables beneficial properties toward remineralization applications such as high wettability and moldability. In light of our results, macroscopic hydrogels are considered for the first time as an ion source for the mineralization of crystalline calcium phosphate phases, representing an entirely new class of preceding mineralization species for potential applications in dentistry and osteology.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acsbiomaterials.1c01090 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!