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Associations of light physical activity, moderate-to-vigorous physical activity and sedentary behavior with quality of life in men on androgen deprivation therapy for prostate cancer: a quantile regression analysis. | LitMetric

AI Article Synopsis

  • - The study analyzed the impact of physical activity (PA) and sedentary time (SED) on the quality of life (QoL) of men undergoing androgen deprivation therapy (ADT) for prostate cancer, involving 106 participants.
  • - Findings showed that more time spent in sedentary activities was linked to higher quality of life scores at the 50th and 75th percentiles, whereas longer SED bouts negatively impacted QoL.
  • - Light-intensity physical activity was positively associated with quality of life, particularly at lower percentiles, indicating that both PA and SED influence QoL differently among men with varying levels of well-being.

Article Abstract

To examine associations of physical activity (PA) and sedentary time (SED) with quality of life (QoL) in men on androgen deprivation therapy (ADT) for prostate cancer. A pooled analysis of 106 men on ADT was conducted. PA and SED were assessed using accelerometers. The Functional Assessment of Cancer Therapy (FACT) was used to assess self-reported QoL. Quantile regression examined the associations of QoL with PA and SED. Total time spent in SED was positively associated with FACT-General at the 50th (p = 0.010) and 75th percentile (p = 0.022). SED in ≥ 30-min bouts was inversely associated with FACT-General at the 50th  (p = 0.025) and 75th percentile (p = 0.029). Breaks in SED were positively associated with physical well-being at the 75th percentile (p = 0.004). Light-intensity PA was positively associated with FACT-Prostate at the 25th percentile (p = 0.020). SED and PA were associated with QoL outcomes, but time in each varied across men reporting the poorest QoL compared to those in the highest QoL distributions.

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Source
http://dx.doi.org/10.1007/s10865-022-00285-7DOI Listing

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