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Engaging Students in a Dialysis Unit: A Pilot Study.
Clin Teach
February 2025
Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Background: Seeking to provide early paediatric nephrology exposure to medical students in the United States, we implemented the Kids In Dialysis, Nephrology Exposure and Education (KIDNEE) club. This club served as an educational intervention in which preclinical medical students were paired with paediatric dialysis patients, as patient buddies.
Approach: Students were recruited for involvement in the club through the medical school Paediatric Interest Group.
Durvalumab and tremelimumab in combination with metronomic oral vinorelbine for recurrent advanced cervical cancer: an open-label phase I/II study.
J Immunother Cancer
January 2025
Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Background: The MOVIE phase I/II trial (NCT03518606) evaluated the safety and antitumor activity of durvalumab and tremelimumab combined with metronomic oral vinorelbine in patients with advanced tumors. We present the results of the recurrent advanced cervical cancer cohort.
Methods: Patients received tremelimumab (intravenously, 75 mg, every four weeks (Q4W); four cycles max) plus durvalumab (intravenously, 1,500 mg, Q4W; 26 cycles max) and metronomic oral vinorelbine (40 mg, every three weeks (3QW)) until disease progression.
[LORENZO'S OIL AND ADRENOLEUKODYSTROPHY EXAMINING AN ARTIFICIAL INTELLIGENCE TOOL INTENDED FOR CONDUCTING LITERATURE SEARCHES AND ANALYSES].
Harefuah
December 2024
Maccabi Healthcare Services Sharon Region, Hebrew University Faculty of Medicine, and Medint Medical Intelligence, Tel Aviv, Israel.
Adrenoleukodystrophy is a genetic metabolic disorder characterized by a heterogeneous phenotype. Its severe form, known as cerebral adrenoleukodystrophy, involves unpredictable cerebral damage and progressive central nervous system deterioration. This rare condition became famous because of a Hollywood movie in which the Italian parents of a child with the condition supposedly discovered a medication for treating the condition.
View Article and Find Full Text PDFImprove myocardial strain estimation based on deformable groupwise registration with a locally low-rank dissimilarity metric.
BMC Med Imaging
December 2024
National Engineering Research Center of Advanced Magnetic Resonance Technologies for Diagnosis and Therapy, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Background: Current mainstream cardiovascular magnetic resonance-feature tracking (CMR-FT) methods, including optical flow and pairwise registration, often suffer from the drift effect caused by accumulative tracking errors. Here, we developed a CMR-FT method based on deformable groupwise registration with a locally low-rank (LLR) dissimilarity metric to improve myocardial tracking and strain estimation accuracy.
Methods: The proposed method, Groupwise-LLR, performs feature tracking by iteratively updating the entire displacement field across all cardiac phases to minimize the sum of the patchwise signal ranks of the deformed movie.
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