Purpose: The present study was aimed to evaluate the agreement on grading normal clivus on MRI among radiologists.
Methods: A retrospective study included patients who underwent MRI brain during January 1, 2015 to October 31, 2019. Two hundred forty-four patients who had no marrow pathology on MRI were included and divided into 8 age groups by decades. Three radiologists independently reviewed the signal intensity of clivus in mid sagittal T1-weighted image. The signal intensity was classified into three grades (Grade I-III). Fleiss' kappa coefficients (k) were calculated to assess interrater agreement.
Results: Of 244 patients, there were 123 (50.4%) males and 121 (49.6%) females. Age ranged from 1 to 79 years old. Clivus Grade II was more frequently reported (> 50%) by radiologists. The agreement (kappa) among all three radiologists on evaluation of clivus irrespective of the grading equals to 0.67 (95%CI: 0.60-0.74). In stratified analyses by the grade of clivus, the kappa values for Grade I to III and were 0.73, 0.62, and 0.69 respectively.
Conclusion: Interrater agreement of MRI evaluation of normal clivus among radiologists was good. The visual grading criteria to classify the clivus is sufficient to distinguish the marrow maturation. However, the consensus reading should be made whenever normal clivus Grade II is read.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760553 | PMC |
| http://dx.doi.org/10.1016/j.ejro.2022.100395 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Ectopic dopamine agonist-resistant macroprolactinoma to the clivus masquerading as a chordoma - A case report.
Endocr Regul
January 2025
1Endocrinology and Internal Medicine Department, Fattouma Bourguiba University Hospital, Monastir, Tunisia.
Pituitary neuroendocrine tumors (PitNETS) are common intracranial tumors, but extrasellar or ectopic PitNETS are very rare and supposed to originate from some pituitary remnants. They are mostly found in sphenoidal sinus. But particularly, ectopic clival PitNETS are highly aggressive and can cause bone invasion and can be misdiagnosed as other lesions of the skull base such as chordomas.
View Article and Find Full Text PDFFibrous Dysplasia of Sphenoid: A Case Report.
Indian J Otolaryngol Head Neck Surg
January 2025
Department of Otorhinolaryngology, Saveetha Medical College and Hospital, SIMATS, Saveetha Nagar, Thandalam, Chennai, Tamil Nadu 602105 India.
Fibrous dysplasia, a rare benign condition with an uncertain cause, is characterized by substituting normal medullary bone with abnormal and weak fibrous and osseous tissue. This primary bone disorder is non-neoplastic and involves a deficiency in osteoblastic differentiation and maturation, which begins in the bone's mesenchymal precursor. A 20-year-old female attended ENT OPD with complaints of headache for 3 years, A diagnostic nasal endoscopy was done which showed no significant abnormalities, and CT PNS was done which showed Extensive sclerotic bony expansion with a ground glass appearance involving the clivus, right greater wing of sphenoid, pterygoid processes - Likely fibrous dysplasia since she had no other signs or symptoms, she was kept under observation.
View Article and Find Full Text PDFClival fibrous dysplasia in which short interval disease progression posed a diagnostic challenge in a skeletally mature patient: a case report.
J Med Case Rep
February 2025
Department of Radiology, Stanford University School of Medicine, Stanford, CA, USA.
Background: Fibrous dysplasia is an uncommon bone disorder in which medullary bone is replaced by disorganized fibro-osseous tissue. Fibrous dysplasia typically exhibits slow growth that stabilizes with skeletal maturity. We report a case in which rapid progression of a clival lesion otherwise typical for fibrous dysplasia in an adult male led to concern for a malignant rather than a benign lesion.
View Article and Find Full Text PDFIntracranial phosphaturic mesenchymal tumor: A rare case report and systematic review.
Medicine (Baltimore)
February 2025
Department of Neurosurgery, Weifang People's Hospital, Shandong Second Medical University, Weifang, China.
Rationale: Phosphaturic mesenchymal tumors (PMTs) are rare soft-tissue and bone tumors that can occur intracranially. Low incidence, nonspecific symptoms, and diverse histomorphology of PMTs contribute to a high rate of misdiagnosis.
Patient Concerns: This report presents a rare case of an intracranial PMT located in the posterior cranial fossa.
Successful Multimodal Management of an Aggressive Functional Gonadotropic Pituitary Macroadenoma.
AACE Clin Case Rep
September 2024
Department of Neurological Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Background/objective: Although most gonadotroph cell-derived pituitary adenomas (PAs) give rise to nonfunctional PAs, hormonally active functional gonadotroph adenomas (FGAs) are exceedingly rare. We present a case of a giant and invasive functional gonadotropic pituitary macroadenoma treated with endoscopic transsphenoidal surgery and subsequent postoperative radiotherapy.
Case Report: A 54-year-old man presented with gradually worsening vision over 1 year.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!